Tag : Untranslated regions

Biology

Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3

Newsemia
by Violeta Heras, Susana Sangiao-Alvarellos, Maria Manfredi-Lozano, María J. Sanchez-Tapia, Francisco Ruiz-Pino, Juan Roa, Maribel Lara-Chica, Rosario Morrugares-Carmona, Nathalie Jouy, Ana P. Abreu, Vincent Prevot,...
Biology

Inverted translational control of eukaryotic gene expression by ribosome collisions

Newsemia
by Heungwon Park, Arvind R. Subramaniam The canonical model of eukaryotic translation posits that efficient translation initiation increases protein expression and mRNA stability. Contrary to...
Biology

A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka

Newsemia
by Amaury Herpin, Cornelia Schmidt, Susanne Kneitz, Clara Gobé, Martina Regensburger, Aurélie Le Cam, Jérome Montfort, Mateus C. Adolfi, Christina Lillesaar, Dagmar Wilhelm, Michael Kraeussling,...
Biology

Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1<sup>p150</sup>

Newsemia
by Christian K. Pfaller, Ryan C. Donohue, Stepan Nersisyan, Leonid Brodsky, Roberto Cattaneo The interferon (IFN)-mediated innate immune response is the first line of defense...
Biology

Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during <i>Drosophila</i> development

Newsemia
by Hong Zhang, Shengqian Dou, Feng He, Junjie Luo, Liping Wei, Jian Lu Upstream open reading frames (uORFs) play important roles in regulating the main...

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