Tag : underlies

Dermatology

Cigarette smoke underlies the pathogenesis of palmoplantar pustulosis via an IL-17A-induced production of IL-36γ in tonsillar epithelial cells

Newsemia
Palmoplantar pustulosis (PPP) is characterized by sterile pustules on the palms and/or soles. A strong association between PPP and tobacco smoking has been reported, and...
Dermatology

Enhanced Thermal Sensitivity of TRPV3 in Keratinocytes Underlies Heat-Induced Pruritogen Release and Pruritus in Atopic Dermatitis

Newsemia
Itch in atopic dermatitis (AD) is aggravated under warm conditions. Transient receptor potential vanilloid (TRPV) 3, a member of the thermosensitive transient receptor potential channels,...
Cardiology

An acute immune response underlies the benefit of cardiac stem-cell therapy.

Newsemia
An acute immune response underlies the benefit of cardiac stem-cell therapy. Nature. 2019 Nov 27;: Authors: Vagnozzi RJ, Maillet M, Sargent MA, Khalil H, Johansen...
Cardiology

Identification of a novel compound heterozygous IDUA mutation underlies Mucopolysaccharidoses type I in a Chinese pedigree.

Newsemia
Related Articles Identification of a novel compound heterozygous IDUA mutation underlies Mucopolysaccharidoses type I in a Chinese pedigree. Mol Genet Genomic Med. 2019 Nov 23;:e1058...
Biology

Protein Melting Temperature Cannot Fully Assess Whether Protein Folding Free Energy Underlies the Universal Abundance–Evolutionary Rate Correlation Seen in Proteins

Newsemia
Abstract The protein misfolding avoidance hypothesis explains the universal negative correlation between protein abundance and sequence evolutionary rate across the proteome by identifying protein folding...
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Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis

Newsemia
Serwas, NK; Hoeger, B; Ardy, RC; Stulz, SV; Sui, Z; Memaran, N; Meeths, M; … Boztug, K; + view all Serwas, NK; Hoeger, B; Ardy,...
Biology

The amplitude in periodic neural state trajectories underlies the tempo of rhythmic tapping

Newsemia
by Jorge Gámez, Germán Mendoza, Luis Prado, Abraham Betancourt, Hugo Merchant Our motor commands can be exquisitely timed according to the demands of the environment,...
Biology

Dynamic Interaction of Eukaryotic Initiation Factor 4G1 (eIF4G1) with eIF4E and eIF1 Underlies Scanning-Dependent and -Independent Translation [Research Article]

Newsemia
Translation initiation of most mRNAs involves m7G-cap binding, ribosomal scanning, and AUG selection. Initiation from an m7G-cap-proximal AUG can be bypassed resulting in leaky scanning,...
Biology

Differential aging of growth plate cartilage underlies differences in bone length and thus helps determine skeletal proportions

Newsemia
by Julian C. Lui, Youn Hee Jee, Presley Garrison, James R. Iben, Shanna Yue, Michal Ad, Quang Nguyen, Bijal Kikani, Yoshiyuki Wakabayashi, Jeffrey Baron Bones...

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