Tag: TYROSINE

AI/ML

Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease.

Newsemia
Related Articles Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson’s disease. Dis Model Mech. 2019 11 22;12(11):...
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Molecular characterisation of CRYPα, an axonal receptor protein tyrosine phosphatase

Newsemia
Aricescu, Alexandru Radu; (2001) Molecular characterisation of CRYPα, an axonal receptor protein tyrosine phosphatase. Doctoral thesis (Ph.D), UCL (University College London). Green open access Source...
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Intracellular trafficking, and function of receptor tyrosine kinases in mammary gland development

Newsemia
Dillon, Christian; (2002) Intracellular trafficking, and function of receptor tyrosine kinases in mammary gland development. Doctoral thesis (Ph.D), UCL (University College London). Green open access...
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New strategy identified to address the underlying cause of LAD1 patients' symptoms

Newsemia
Owing to a rare genetic mutation, individuals with leukocyte adhesion deficiency type 1 (LAD1) experience a suite of symptoms that trace back to an immune...
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Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

Newsemia
Oncotarget Volume 11, Issue 11 reported that at clinical progression, 64 EGFR T790M plasma positive patients were subjected to second line-treatment with osimertinib and strictly...
Pharma / Biotech

Safety, Pharmacokinetics and Pharmacodynamics of Branebrutinib (BMS-986195), a Covalent, Irreversible Inhibitor of Bruton's Tyrosine Kinase: Randomised Phase I, Placebo-Controlled Trial in Healthy Participants.

Newsemia
Safety, Pharmacokinetics and Pharmacodynamics of Branebrutinib (BMS-986195), a Covalent, Irreversible Inhibitor of Bruton’s Tyrosine Kinase: Randomised Phase I, Placebo-Controlled Trial in Healthy Participants. Br J...
Biology

The receptor tyrosine kinase Ror is required for dendrite regeneration in <i>Drosophila</i> neurons

Newsemia
by Derek M. R. Nye, Richard M. Albertson, Alexis T. Weiner, J. Ian Hertzler, Matthew Shorey, Deborah C. I. Goberdhan, Clive Wilson, Kevin A. Janes,...
Pharma / Biotech

Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician's perspective.

Newsemia
Related Articles Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician’s perspective. Daru. 2020 Jan 03;: Authors: Pushpam D, Bakhshi S Abstract OBJECTIVE:...
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Irutinib-based therapy provides superior clinical outcomes in majority of CLL patients

Newsemia
The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) today announced results from an extended follow-up analysis of patients in its randomized Phase 3 clinical trial, E1912. Source...
Biology

Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus

Newsemia
by Hye-Yeoung Yun, Min Wook Kim, Hye Seon Lee, Wantae Kim, Ji Hye Shin, Hyunmin Kim, Ho-Chul Shin, Hwangseo Park, Byung-Ha Oh, Won Kon Kim,...
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Bio-Rad launches new digital PCR system and kit for monitoring treatment response in CML patients

Newsemia
Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, today announced that its QXDx AutoDG ddPCR System, which uses Bio-Rad’s...
Gastroenterology

Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma

Newsemia
Integrated analysis of multiple receptor tyrosine kinases identifies Axl as a therapeutic target and mediator of resistance to sorafenib in hepatocellular carcinoma Source link...

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