Tag : tumorigenesis

Biology

Long Noncoding RNA H19 Promotes Tumorigenesis of Multiple Myeloma by Activating BRD4 Signaling by Targeting MicroRNA 152-3p [Research Article]

Newsemia
Multiple myeloma (MM) accounts for over twenty percent of hematological cancer-related death worldwide. Long noncoding RNA (lncRNA) H19 is associated with multiple tumorigenesis and is...
Gastroenterology

The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in Mice

Newsemia
The histone lysine demethylase 3A (KDM3A) demethylates demethylates H3K9me1 and H3K9Me2 to increase gene transcription and is upregulated in tumors, including pancreatic tumors. We investigated...
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RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury

Newsemia
Krishna-Subramanian, S; Singer, S; Armaka, M; Banales, JM; Holzer, K; Schirmacher, P; Walczak, H; … Kondylis, V; + view all Krishna-Subramanian, S; Singer, S; Armaka,...
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Researchers unravel the biology of how obesity promotes triple-negative breast cancer

Newsemia
Smoking has long been the biggest cause of cancer in the United States, but obesity, now the second leading cause, has been gaining ground. Source...
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Scientists discover biological barrier that keeps cancer at bay

Newsemia
Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune...

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