Tag : Transporter

Biology

Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment [SHORT COMMUNICATION]

Newsemia
Petra M. Hermann, Alexander C. Perry, Izen Hamad, and Willem C. Wildering Plasma membrane efflux transporters play crucial roles in the removal and release of...
Biology

Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment [SHORT COMMUNICATION]

Newsemia
Petra M. Hermann, Alexander C. Perry, Izen Hamad, and Willem C. Wildering Plasma membrane efflux transporters play crucial roles in the removal and release of...
Cardiology

Affinity, binding kinetics and functional characterization of draflazine analogues for human Equilibrative Nucleoside Transporter 1 (SLC29A1).

Newsemia
Related Articles Affinity, binding kinetics and functional characterization of draflazine analogues for human Equilibrative Nucleoside Transporter 1 (SLC29A1). Biochem Pharmacol. 2019 Dec 09;:113747 Authors: Vlachodimou...
Cardiology

Serotonin uptake via plasma membrane monoamine transporter during myocardial ischemia-reperfusion in the rat heart in vivo.

Newsemia
Related Articles Serotonin uptake via plasma membrane monoamine transporter during myocardial ischemia-reperfusion in the rat heart in vivo. Physiol Rep. 2019 Nov;7(22):e14297 Authors: Sonobe T,...
Pediatrics

Understanding Transporter Proteins at a Single-Molecule Level

Newsemia
Research co-led by a St. Jude investigator and researchers from Columbia University and the New York State Psychiatric Institute reveals the mechanics of how some...
Gastroenterology

ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells

Newsemia
Pancreatic tumors undergo rapid growth and progression, become resistant to chemotherapy, and recur after surgery. We studied the functions of the solute carrier family 39...
Pharma / Biotech

Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability.

Newsemia
Related Articles Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability....
Biology

1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol Attenuates Streptozotocin-Induced Pancreatic Beta Cell Damage by Promoting Glucose Transporter 2 Endocytosis [Research Article]

Newsemia
Streptozotocin (STZ) is widely used to induce diabetic rodent models. It is specifically toxic to pancreatic beta cells and causes severe destruction and dysfunction. We...

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