Tag: Transporter

Pharma / Biotech

Concomitant lansoprazole ameliorates cisplatin-induced nephrotoxicity by inhibiting renal organic cation transporter 2 in rats.

Newsemia
Related Articles Concomitant lansoprazole ameliorates cisplatin-induced nephrotoxicity by inhibiting renal organic cation transporter 2 in rats. Biopharm Drug Dispos. 2020 May 30;: Authors: Hiramatsu SI,...
Gastroenterology

Creatine Transporter, Reduced in Colon Tissues From Patients With Inflammatory Bowel Diseases, Regulates Energy Balance in Intestinal Epithelial Cells, Epithelial Integrity, and Barrier Function

Newsemia
Patients with inflammatory bowel diseases (IBD) have intestinal barrier dysfunction. Creatine regulates energy distribution within cells and reduces the severity of colitis in mice. We...
Latest News

Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of Streptococcus pneumoniae Associated with Distinct Alleles of the Type I Restriction-Modification System

Newsemia
Durmort, C; Ercoli, G; Ramos-Sevillano, E; Chimalapati, S; Haigh, RD; De Ste Croix, M; Gould, K; … Brown, JS; + view all Durmort, C; Ercoli,...
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Prediction of Clinical Transporter Mediated Drug‐Drug Interactions via Co‐measurement of Pitavastatin and Eltrombopag in Human Hepatocyte Models

Newsemia
Carter, SJ; Chouhan, B; Sharma, P; Chappell, MJ; (2020) Prediction of Clinical Transporter Mediated Drug‐Drug Interactions via Co‐measurement of Pitavastatin and Eltrombopag in Human Hepatocyte...
Biology

Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment [SHORT COMMUNICATION]

Newsemia
Petra M. Hermann, Alexander C. Perry, Izen Hamad, and Willem C. Wildering Plasma membrane efflux transporters play crucial roles in the removal and release of...
Biology

Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment [SHORT COMMUNICATION]

Newsemia
Petra M. Hermann, Alexander C. Perry, Izen Hamad, and Willem C. Wildering Plasma membrane efflux transporters play crucial roles in the removal and release of...
Cardiology

Affinity, binding kinetics and functional characterization of draflazine analogues for human Equilibrative Nucleoside Transporter 1 (SLC29A1).

Newsemia
Related Articles Affinity, binding kinetics and functional characterization of draflazine analogues for human Equilibrative Nucleoside Transporter 1 (SLC29A1). Biochem Pharmacol. 2019 Dec 09;:113747 Authors: Vlachodimou...
Cardiology

Serotonin uptake via plasma membrane monoamine transporter during myocardial ischemia-reperfusion in the rat heart in vivo.

Newsemia
Related Articles Serotonin uptake via plasma membrane monoamine transporter during myocardial ischemia-reperfusion in the rat heart in vivo. Physiol Rep. 2019 Nov;7(22):e14297 Authors: Sonobe T,...
Pediatrics

Understanding Transporter Proteins at a Single-Molecule Level

Newsemia
Research co-led by a St. Jude investigator and researchers from Columbia University and the New York State Psychiatric Institute reveals the mechanics of how some...
Gastroenterology

ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells

Newsemia
Pancreatic tumors undergo rapid growth and progression, become resistant to chemotherapy, and recur after surgery. We studied the functions of the solute carrier family 39...

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