Translational

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development Source link

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‘Health shall have no borders:’ ISB’s Dr. Qiang Tian Joins Shanghai’s National Research Center for Translational Medicine

At the turn of the century, Dr. Qiang Tian signed on as a postdoctoral fellow with legendary scientist Dr. Lee Hood. He was in for a wild ride. In 2000,...

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Translational inhibition of α-synuclein by Posiphen normalizes distal colon motility in transgenic Parkinson mice.

Related Articles Translational inhibition of α-synuclein by Posiphen normalizes distal colon motility in transgenic Parkinson mice. Am J Neurodegener Dis. 2019;8(1):1-15 Authors: Kuo YM, Nwankwo EI, Nussbaum RL, Rogers J,...

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Translational methods to detect asymmetries in temporal and spatial walking metrics in parkinsonian mouse models and human subjects with Parkinson’s disease

[ad_1] Translational methods to detect asymmetries in temporal and spatial walking metrics in parkinsonian mouse models and human subjects with Parkinson’s disease Source link [ad_2]

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Using deep learning to identify translational research in genomic medicine beyond bench to bedside.

[ad_1] Related Articles Using deep learning to identify translational research in genomic medicine beyond bench to bedside. Database (Oxford). 2019 Jan 01;2019: Authors: Hsu YY, Clyne M, Wei CH, Khoury...

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LEO Pharma Strengthens Focus on Translational Medicine with the Appointment of Adam B. Raff, M.D., Ph.D., as Director and Medical Advisor

[ad_1] BALLERUP, Denmark--(BUSINESS WIRE)--LEO Pharma, a global leader in medical dermatology, today announced that Adam B. Raff has been appointed as Director and Medical Advisor in Translational Medicine as of...

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Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research?

[ad_1] Related Articles Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research?...

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From Endogenous Compounds as Biomarkers to Plasma-Derived Nanovesicles as Liquid Biopsy; Has the Golden Age of Translational PK-ADME-DDI Science Finally Arrived?

[ad_1] Related Articles From Endogenous Compounds as Biomarkers to Plasma-Derived Nanovesicles as Liquid Biopsy; Has the Golden Age of Translational PK-ADME-DDI Science Finally Arrived? Clin Pharmacol Ther. 2018 Dec 16;:...

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DDX3 Participates in Translational Control of Inflammation Induced by Infections and Injuries [Research Article]

[ad_1] Recent studies have suggested that DDX3 functions in antiviral innate immunity, but the underlying mechanism remains elusive. We previously identified target mRNAs whose translation is controlled by DDX3. Pathway...

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Translational Research: Bringing Science to the Provider Through Guideline Implementation.

[ad_1] Related Articles Translational Research: Bringing Science to the Provider Through Guideline Implementation. Dent Clin North Am. 2019 Jan;63(1):129-144 Authors: Frantsve-Hawley J, Rindal DB Abstract Significant variation exists in health...

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Spotlight on James Yurkovich, ISB Translational Research Fellow

[ad_1] Dr. James Yurkovich joined ISB this summer as a Translational Research Fellow. The three-year Translational Research Fellows Program provides a unique opportunity for bench-to-bedside translational research with mentorship from...

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Translational science: drawing the line

[ad_1] Humankind has been researching and engineering for as long as we have existed. It was a matter of survival back then and it is still is nowadays. This long...

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Tufts CTSI and Novartis collaborate to foster innovative translational research

[ad_1] Leaders from Tufts Clinical and Translational Science Institute and Novartis announced today a new collaboration to work together to foster innovative translational research and improve health through the exchange...

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Melatonin as an adjunct to therapeutic hypothermia in a piglet model of neonatal encephalopathy: A translational study.

Related Articles Melatonin as an adjunct to therapeutic hypothermia in a piglet model of neonatal encephalopathy: A translational study. Neurobiol Dis. 2018 Oct 06;: Authors: Robertson NJ, Martinello K, Lingam...

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Translational machine learning for psychiatric neuroimaging.

Translational machine learning for psychiatric neuroimaging. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Oct 02;: Authors: Walter M, Alizadeh S, Jamalabadi H, Lueken U, Dannlowski U, Walter H, Olbrich S, Colic L,...

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David Sun Lecture – Translational Approaches to Common GI Diseases… Thinking Out of the Box…The Future is Now!

DAVID SUN LECTURE David A. Johnson, MD, MACG Translational Approaches to Common GI Diseases…Thinking Out of the Box…The Future is Now! Saturday, October 6 | 10:00 am – 10:30 am...

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Lso2 is a conserved ribosome-bound protein required for translational recovery in yeast

by Yinuo J. Wang, Pavanapuresan P. Vaidyanathan, Maria F. Rojas-Duran, Namrata D. Udeshi, Kristen M. Bartoli, Steven A. Carr, Wendy V. Gilbert Ribosome-binding proteins function broadly in protein synthesis, gene...

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Currents of memory: recent progress, translational challenges, and ethical considerations in fornix deep brain stimulation trials for Alzheimer's disease.

Related Articles Currents of memory: recent progress, translational challenges, and ethical considerations in fornix deep brain stimulation trials for Alzheimer's disease. Neurobiol Aging. 2017 Aug;56:202-210 Authors: Viaña JNM, Vickers JC,...

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Nonataxia symptoms in Friedreich Ataxia: Report from the Registry of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS)

Objective To provide a systematic evaluation of the broad clinical variability in Friedreich ataxia (FRDA), a multisystem disorder presenting mainly with afferent ataxia but also a complex phenotype of nonataxia...

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Taking a Pill Can Effectively Treat Brutal Lung Disease

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis...

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