Tag : transgenic

AI/ML

Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer's Disease Pathology.

Newsemia
Related Articles Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer’s Disease Pathology. Cereb Cortex. 2019 06 01;29(6):2716-2727 Authors: Stoiljkovic M, Kelley C, Stutz...
AI/ML

Longitudinal assessment of the neuroanatomical consequences of deep brain stimulation: Application of fornical DBS in an Alzheimer's mouse model.

Newsemia
Related Articles Longitudinal assessment of the neuroanatomical consequences of deep brain stimulation: Application of fornical DBS in an Alzheimer’s mouse model. Brain Res. 2019 07...
AI/ML

Loss of Midbrain Dopamine Neurons and Altered Apomorphine EEG Effects in the 5xFAD Mouse Model of Alzheimer's Disease.

Newsemia
Related Articles Loss of Midbrain Dopamine Neurons and Altered Apomorphine EEG Effects in the 5xFAD Mouse Model of Alzheimer’s Disease. J Alzheimers Dis. 2019;70(1):241-256 Authors:...
Cardiology

MCU Up-regulation contributes to myocardial ischemia-reperfusion Injury through calpain/OPA-1-mediated mitochondrial fusion/mitophagy Inhibition.

Newsemia
Related Articles MCU Up-regulation contributes to myocardial ischemia-reperfusion Injury through calpain/OPA-1-mediated mitochondrial fusion/mitophagy Inhibition. J Cell Mol Med. 2019 11;23(11):7830-7843 Authors: Guan L, Che Z,...
Cardiology

Chitosan Hydrogel Enhances the Therapeutic Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells for Myocardial Infarction by Alleviating Vascular Endothelial Cell Pyroptosis.

Newsemia
Related Articles Chitosan Hydrogel Enhances the Therapeutic Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells for Myocardial Infarction by Alleviating Vascular Endothelial Cell Pyroptosis. J Cardiovasc...
AI/ML

Circadian dysfunction in the Q175 model of Huntington's disease: Network analysis.

Newsemia
Related Articles Circadian dysfunction in the Q175 model of Huntington’s disease: Network analysis. J Neurosci Res. 2019 12;97(12):1606-1623 Authors: Smarr B, Cutler T, Loh DH,...
Cardiology

The BD2 domain of BRD4 is a determinant in EndoMT and vein graft neointima formation.

Newsemia
Related Articles The BD2 domain of BRD4 is a determinant in EndoMT and vein graft neointima formation. Cell Signal. 2019 09;61:20-29 Authors: Zhang M, Wang...
AI/ML

Regional differences in Alzheimer's disease pathology confound behavioural rescue after amyloid-β attenuation.

Newsemia
Related Articles Regional differences in Alzheimer’s disease pathology confound behavioural rescue after amyloid-β attenuation. Brain. 2020 01 01;143(1):359-373 Authors: Morrone CD, Bazzigaluppi P, Beckett TL,...
Pharma / Biotech

Anisotropic poly(lactic-co-glycolic acid) microparticles enable sustained release of a peptide for long-term inhibition of ocular neovascularization.

Newsemia
Related Articles Anisotropic poly(lactic-co-glycolic acid) microparticles enable sustained release of a peptide for long-term inhibition of ocular neovascularization. Acta Biomater. 2019 10 01;97:451-460 Authors: Kim...
AI/ML

Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer's Disease.

Newsemia
Related Articles Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease. Neural Plast. 2019;2019:6981268 Authors: Ahnaou...
Biology

Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS

Newsemia
by Emmanuel A. Asante, Jacqueline M. Linehan, Andrew Tomlinson, Tatiana Jakubcova, Shyma Hamdan, Andrew Grimshaw, Michelle Smidak, Asif Jeelani, Akin Nihat, Simon Mead, Sebastian Brandner,...
Neurology

An Ultra High Performance Liquid Chromatography-High Resolution Mass Spectrometry Metabolomics and Lipidomics Study of Stool from Transgenic Parkinson’s Disease Mice Following Immunotherapy

Newsemia
Congratulations Drs. Okun and Vedam-Mai. on the publication of “An Ultra High Performance Liquid Chromatography-High Resolution Mass Spectrometry Metabolomics and Lipidomics Study of Stool from...

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