Tag : transcriptome

Gastroenterology

Identification of Subtypes of Barrett’s Esophagus and Esophageal Adenocarcinoma Based on DNA Methylation Profiles and Integration of Transcriptome and Genome Data

Newsemia
Esophageal adenocarcinomas (EAC) are heterogeneous and often preceded by Barrett’s esophagus (BE). Many genomic changes have been associated with development of BE and EAC, but...
Gastroenterology

Global transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss

Newsemia
Global transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss Source link...
Gastroenterology

Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on single-cell Transcriptome Analyses

Newsemia
It has been a challenge to develop fully functioning cells from human pluripotent stem cells (hPSCs). We investigated how activation of hedgehog signaling regulates derivation...
Biology

Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

Newsemia
by Oliver Smith, Glenn Dunshea, Mikkel-Holger S. Sinding, Sergey Fedorov, Mietje Germonpre, Hervé Bocherens, M. T. P. Gilbert While sequencing ancient DNA (aDNA) from archaeological...
Biology

Dissecting the transcriptome landscape of the human fetal neural retina and retinal pigment epithelium by single-cell RNA-seq analysis

Newsemia
by Yuqiong Hu, Xiaoye Wang, Boqiang Hu, Yunuo Mao, Yidong Chen, Liying Yan, Jun Yong, Ji Dong, Yuan Wei, Wei Wang, Lu Wen, Jie Qiao,...
Pediatrics

New Computational Tool Harnesses Big Data and Deep Learning to Illuminate 'Dark Matter' of the Transciptome

Newsemia
A research team at Children’s Hospital of Philadelphia has developed an innovative computational tool offering researchers an efficient method for detecting the different ways RNA...

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