Tag : Transcriptome analysis

Biology

A single-cell atlas of adult <i>Drosophila</i> ovary identifies transcriptional programs and somatic cell lineage regulating oogenesis

Newsemia
by Allison Jevitt, Deeptiman Chatterjee, Gengqiang Xie, Xian-Feng Wang, Taylor Otwell, Yi-Chun Huang, Wu-Min Deng Oogenesis is a complex developmental process that involves spatiotemporally regulated...
Biology

Single-cell transcription analysis of <i>Plasmodium vivax</i> blood-stage parasites identifies stage- and species-specific profiles of expression

Newsemia
by Juliana M. Sà, Matthew V. Cannon, Ramoncito L. Caleon, Thomas E. Wellems, David Serre Plasmodium vivax and P. falciparum, the parasites responsible for most...
Biology

YTHDF2 promotes mitotic entry and is regulated by cell cycle mediators

Newsemia
by Qili Fei, Zhongyu Zou, Ian A. Roundtree, Hui-Lung Sun, Chuan He The N6-methyladenosine (m6A) modification regulates mRNA stability and translation. Here, we show that...
Biology

Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform

Newsemia
by Charles Blatti III, Amin Emad, Matthew J. Berry, Lisa Gatzke, Milt Epstein, Daniel Lanier, Pramod Rizal, Jing Ge, Xiaoxia Liao, Omar Sobh, Mike Lambert,...
Biology

A proteomic atlas of senescence-associated secretomes for aging biomarker development

Newsemia
by Nathan Basisty, Abhijit Kale, Ok Hee Jeon, Chisaka Kuehnemann, Therese Payne, Chirag Rao, Anja Holtz, Samah Shah, Vagisha Sharma, Luigi Ferrucci, Judith Campisi, Birgit...
Biology

Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias

Newsemia
by Shir Mandelboum, Zohar Manber, Orna Elroy-Stein, Ran Elkon Data normalization is a critical step in RNA sequencing (RNA-seq) analysis, aiming to remove systematic effects...
Biology

Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

Newsemia
by Oliver Smith, Glenn Dunshea, Mikkel-Holger S. Sinding, Sergey Fedorov, Mietje Germonpre, Hervé Bocherens, M. T. P. Gilbert While sequencing ancient DNA (aDNA) from archaeological...
Biology

Human visual cortex is organized along two genetically opposed hierarchical gradients with unique developmental and evolutionary origins

Newsemia
by Jesse Gomez, Zonglei Zhen, Kevin S. Weiner Human visual cortex is organized with striking consistency across individuals. While recent findings demonstrate an unexpected coupling...
Biology

Dissecting the transcriptome landscape of the human fetal neural retina and retinal pigment epithelium by single-cell RNA-seq analysis

Newsemia
by Yuqiong Hu, Xiaoye Wang, Boqiang Hu, Yunuo Mao, Yidong Chen, Liying Yan, Jun Yong, Ji Dong, Yuan Wei, Wei Wang, Lu Wen, Jie Qiao,...

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