Tag: transcription

Gastroenterology

Activating Transcription Factor 6 Mediates Inflammatory Signals in Intestinal Epithelial Cells Upon Endoplasmic Reticulum Stress

Newsemia
Excess and unresolved endoplasmic reticulum (ER) stress in intestinal epithelial cells (IECs) promotes intestinal inflammation. Activating transcription factor 6 (ATF6) is one of the signaling...
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Zinc-finger transcription factors in the Schwann cell lineage

Newsemia
Harris, Brett Stuart; (2001) Zinc-finger transcription factors in the Schwann cell lineage. Doctoral thesis (Ph.D), UCL (University College London). Green open access Source link...
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SARS-CoV-2 infection modeling in iPSC-derived type 2 cells

Newsemia
The most fatal form of COVID-19 disease is acute respiratory distress syndrome (ARDS), caused by direct viral injury as well as indirect noxious effects caused...
Gastroenterology

TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines

Newsemia
We investigated the transcriptome of esophageal squamous cell carcinoma (ESCC) cells, activity of gene regulatory (enhancer and promoter regions), and the effects of blocking epigenetic...
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The transcription factors dHAND and eHAND and the growth factor HGF are involved in peripheral nervous system development

Newsemia
Dean, Charlotte Hannah; (2001) The transcription factors dHAND and eHAND and the growth factor HGF are involved in peripheral nervous system development. Doctoral thesis (Ph.D),...
Gastroenterology

The Transcription co-Repressors MTG8 and MTG16 Regulate Exit of Intestinal Stem Cells From Their Niche and Differentiation into Enterocyte vs Secretory Lineages

Newsemia
Notch signaling maintains intestinal stem cells (ISCs). When ISCs exit the niche, Notch signaling among early progenitor cells at position +4/5 regulates their specification toward...
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Study provides molecular explanation to a longstanding mystery in viral oncology

Newsemia
The oncogenic herpesvirus (HHV8 or KSHV) causes a cancer known as Kaposi’s Sarcoma. An international team of scientists led by the University of Helsinki has...
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GMU researchers studying effect of cannabidiol on exosome release

Newsemia
Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally...
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SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

Newsemia
In their recent paper released on the bioRxiv preprint server, a research group from Spain demonstrated how genome changes and deletions in severe acute respiratory...
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ACE2 receptors for SARS-CoV-2 in human eye

Newsemia
Since its emergence in Wuhan, China, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly over most of the world’s inhabited regions, causing...
Biology

Transcription Factors FHY3 and FAR1 Regulate Light-Induced CIRCADIAN CLOCK ASSOCIATED1 Gene Expression in Arabidopsis

Newsemia
The circadian clock provides a time-keeping mechanism that synchronizes various biological activities with the surrounding environment. Arabidopsis (Arabidopsis thaliana) CIRCADIAN CLOCK ASSOCIATED1 (CCA1), encoding a...
Biology

Single-cell transcription analysis of <i>Plasmodium vivax</i> blood-stage parasites identifies stage- and species-specific profiles of expression

Newsemia
by Juliana M. Sà, Matthew V. Cannon, Ramoncito L. Caleon, Thomas E. Wellems, David Serre Plasmodium vivax and P. falciparum, the parasites responsible for most...

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