Tag: TIGIT

Gastroenterology

Hepatocellular Carcinoma Cells Upregulate PVRL1, Stabilizing PVR and Inhibiting the Cytotoxic T-cell Response via TIGIT to Mediate Tumor Resistance to PD1 Inhibitors in Mice

Newsemia
Immune checkpoint inhibitors are effective in treatment of some hepatocellular carcinomas (HCCs), but these tumors do not always respond to inhibitors of programmed cell death...
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Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT

Newsemia
Gilbert, RM; Zhang, X; Sampson, RD; Ehrenstein, MR; Nguyen, DX; Chaudhry, M; Mein, C; … Lightman, S; + view all Gilbert, RM; Zhang, X; Sampson,...

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