Tag : Tcell

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Chimeric antigen receptor T-cell therapy for haematological malignancies.

Newsemia
Chimeric antigen receptor T-cell therapy for haematological malignancies. Med J Aust. 2020 Sep 20;: Authors: Selim AG, Tam CS PMID: 32951222 [PubMed – as supplied...
Cardiology

A peripheral T-cell lymphoma (PTCL) arising as a post-transplant lymphoproliferative disorder: efficacy of pralatrexate in primary refractory disease and review of the literature.

Newsemia
Related Articles A peripheral T-cell lymphoma (PTCL) arising as a post-transplant lymphoproliferative disorder: efficacy of pralatrexate in primary refractory disease and review of the literature....
Cardiology

Adaptive immune disorders in hypertension and heart failure: focusing on T-cell subset activation and clinical implications.

Newsemia
Related Articles Adaptive immune disorders in hypertension and heart failure: focusing on T-cell subset activation and clinical implications. J Hypertens. 2020 Oct;38(10):1878-1889 Authors: Rai A,...
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Engineering Solutions for Mitigation of Chimeric Antigen Receptor T-Cell Dysfunction

Newsemia
Gavriil, A; Barisa, M; Halliwell, E; Anderson, J; (2020) Engineering Solutions for Mitigation of Chimeric Antigen Receptor T-Cell Dysfunction. Cancers , 12 (8) , Article...
Gastroenterology

Hepatocellular Carcinoma Cells Upregulate PVRL1, Stabilizing PVR and Inhibiting the Cytotoxic T-cell Response via TIGIT to Mediate Tumor Resistance to PD1 Inhibitors in Mice

Newsemia
Immune checkpoint inhibitors are effective in treatment of some hepatocellular carcinomas (HCCs), but these tumors do not always respond to inhibitors of programmed cell death...
Biology

IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics

Newsemia
by Candelas Álvarez-Salamero, Raquel Castillo-González, Gloria Pastor-Fernández, Isabel R. Mariblanca, Jesús Pino, Danay Cibrian, María N. Navarro Interleukin 23 (IL-23) triggers pathogenic features in pro-inflammatory,...
Biology

Yap suppresses T-cell function and infiltration in the tumor microenvironment

Newsemia
by Eleni Stampouloglou, Nan Cheng, Anthony Federico, Emily Slaby, Stefano Monti, Gregory L. Szeto, Xaralabos Varelas A major challenge for cancer immunotherapy is sustaining T-cell...

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