Tag : Targeting

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Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70‐Positive Tumors for Multimodal Cancer Theranostics

Newsemia
Shevtsov, M; Stangl, S; Nikolaev, B; Yakovleva, L; Marchenko, Y; Tagaeva, R; Sievert, W; … Multhoff, G; + view all Shevtsov, M; Stangl, S; Nikolaev,...
Pharma / Biotech

Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice.

Newsemia
Related Articles Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice. Biomed Pharmacother. 2020 Jan 29;125:109936 Authors: Chen M, Zhou C, Xu H, Zhang...
Cardiology

MicroRNA-144 Regulates Cardiomyocyte Proliferation and Apoptosis by Targeting TBX1 through the JAK2/STAT1 Pathway.

Newsemia
Related Articles MicroRNA-144 Regulates Cardiomyocyte Proliferation and Apoptosis by Targeting TBX1 through the JAK2/STAT1 Pathway. Cytogenet Genome Res. 2020 Jan 24;: Authors: Cao ML, Zhu...
Pharma / Biotech

Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1.

Newsemia
Related Articles Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1. Clin Pharmacol Ther. 2020 Jan...
Biology

Long Noncoding RNA H19 Promotes Tumorigenesis of Multiple Myeloma by Activating BRD4 Signaling by Targeting MicroRNA 152-3p [Research Article]

Newsemia
Multiple myeloma (MM) accounts for over twenty percent of hematological cancer-related death worldwide. Long noncoding RNA (lncRNA) H19 is associated with multiple tumorigenesis and is...
Cardiology

MicroRNA-486-5p down-regulation protects cardiomyocytes against hypoxia-induced cell injury by targeting IGF-1.

Newsemia
Related Articles MicroRNA-486-5p down-regulation protects cardiomyocytes against hypoxia-induced cell injury by targeting IGF-1. Int J Clin Exp Pathol. 2019;12(7):2544-2551 Authors: Fan J, Shi S, Qiu...
Cardiology

EIF4A3-Induced circ-BNIP3 Aggravated Hypoxia-Induced Injury of H9c2 Cells by Targeting miR-27a-3p/BNIP3.

Newsemia
Related Articles EIF4A3-Induced circ-BNIP3 Aggravated Hypoxia-Induced Injury of H9c2 Cells by Targeting miR-27a-3p/BNIP3. Mol Ther Nucleic Acids. 2019 Nov 26;19:533-545 Authors: Li Y, Ren S,...

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