Tag: Synapses

AI/ML

Engineers put tens of thousands of artificial brain synapses on a single chip

Newsemia
MIT engineers have designed a “brain-on-a-chip,” smaller than a piece of confetti, that is made from tens of thousands of artificial brain synapses known as...
Biology

Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice

Newsemia
by Wangyong Shin, Kyungdeok Kim, Benjamin Serraz, Yi Sul Cho, Doyoun Kim, Muwon Kang, Eun-Jae Lee, Hyejin Lee, Yong Chul Bae, Pierre Paoletti, Eunjoon Kim...
Biology

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons

Newsemia
by Jelmer Willems, Arthur P. H. de Jong, Nicky Scheefhals, Eline Mertens, Lisa A. E. Catsburg, Rogier B. Poorthuis, Fred de Winter, Joost Verhaagen, Frank...
Biology

Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration

Newsemia
by Marta Portela, Varun Venkataramani, Natasha Fahey-Lozano, Esther Seco, Maria Losada-Perez, Frank Winkler, Sergio Casas-Tintó Glioblastoma (GB) is the most lethal brain tumor, and Wingless...
AI/ML

Bio-circuitry mimics synapses and neurons in a step toward sensory computing

Newsemia
Researchers have demonstrated bio-inspired devices that accelerate routes to neuromorphic, or brain-like, computing. Their discovery could support the emergence of computing networks modeled on biology...
Biology

TRPC channels regulate Ca<sup>2+</sup>-signaling and short-term plasticity of fast glutamatergic synapses

Newsemia
by Yvonne Schwarz, Katharina Oleinikov, Barbara Schindeldecker, Amanda Wyatt, Petra Weißgerber, Veit Flockerzi, Ulrich Boehm, Marc Freichel, Dieter Bruns Transient receptor potential (TRP) proteins form...
Biology

Strong preference for autaptic self-connectivity of neocortical PV interneurons facilitates their tuning to γ-oscillations

Newsemia
by Charlotte Deleuze, Gary S. Bhumbra, Antonio Pazienti, Joana Lourenço, Caroline Mailhes, Andrea Aguirre, Marco Beato, Alberto Bacci Parvalbumin (PV)-positive interneurons modulate cortical activity through...
Biology

Astroglial dysfunctions drive aberrant synaptogenesis and social behavioral deficits in mice with neonatal exposure to lengthy general anesthesia

Newsemia
by Bin Zhou, Lingmin Chen, Ping Liao, Lu Huang, Zhuo Chen, Daqing Liao, Linghui Yang, Jing Wang, Guoqiang Yu, Li Wang, Jianguo Zhang, Yunxia Zuo,...
Biology

Differential role of pre- and postsynaptic neurons in the activity-dependent control of synaptic strengths across dendrites

Newsemia
by Mathieu Letellier, Florian Levet, Olivier Thoumine, Yukiko Goda Neurons receive a large number of active synaptic inputs from their many presynaptic partners across their...
Biology

NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors

Newsemia
by Hyejin Lee, Wangyong Shin, Kyungdeok Kim, Suho Lee, Eun-Jae Lee, Jihye Kim, Hanseul Kweon, Eunee Lee, Haram Park, Muwon Kang, Esther Yang, Hyun Kim,...
Latest News

Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple synapses in situ

Newsemia
Jensen, TP; Zheng, K; Cole, N; Marvin, JS; Looger, LL; Rusakov, DA; (2019) Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple...
AI/ML

Dendritic and Axonal Propagation Delays Determine Emergent Structures of Neuronal Networks with Plastic Synapses.

Newsemia
Related Articles Dendritic and Axonal Propagation Delays Determine Emergent Structures of Neuronal Networks with Plastic Synapses. Sci Rep. 2017 01 03;7:39682 Authors: Madadi Asl M,...

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