Tag: Switch

Biology

Immunoglobulin Class Switch Recombination Is Initiated by Rare Cytosine Deamination Events at Switch Regions [Research Article]

Newsemia
Activation-induced cytidine deaminase (AID) initiates immunoglobulin (Ig) class switch recombination (CSR), somatic hypermutation (SHM), and gene conversion by converting DNA cytosines to uracils at specific...
Biology

A wake-active locomotion circuit depolarizes a sleep-active neuron to switch on sleep

Newsemia
by Elisabeth Maluck, Inka Busack, Judith Besseling, Florentin Masurat, Michal Turek, Karl Emanuel Busch, Henrik Bringmann Sleep-active neurons depolarize during sleep to suppress wakefulness circuits....
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A switch from high-fat to normal diet does not restore sperm quality but prevents metabolic syndrome

Newsemia
Crisóstomo, L; Rato, L; Jarak, I; Silva, BM; Raposo, JF; Batterham, RL; Oliveira, PF; Crisóstomo, L; Rato, L; Jarak, I; Silva, BM; Raposo, JF; Batterham,...

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