Tag: subunit

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Conditional activation of the N598R point mutation in the NR1 subunit of the NMDA receptor in knock-in mice

Newsemia
Rudhard, York; (2001) Conditional activation of the N598R point mutation in the NR1 subunit of the NMDA receptor in knock-in mice. Doctoral thesis (Ph.D), UCL...
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GABAA/benzodiazepine receptor distribution and subunit mRNA expression in human temporal lobe epilepsy

Newsemia
Hand, Kieran Sean Patrick; (1998) GABAA/benzodiazepine receptor distribution and subunit mRNA expression in human temporal lobe epilepsy. Doctoral thesis (Ph.D.), University College London (United Kingdom)....
Biology

An F-Box Protein, Mdm30, Interacts with TREX Subunit Sub2 To Regulate Cellular Abundance Cotranscriptionally in Orchestrating mRNA Export Independently of Splicing and Mitochondrial Function [Research Article]

Newsemia
Although an F-box protein, Mdm30, is found to regulate ubiquitylation of the Sub2 component of TREX (transcription-export) complex for proteasomal degradation in stimulation of mRNA...
Cardiology

Cardiac ischemia/reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα.

Newsemia
Cardiac ischemia/reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα. Am J Physiol Heart Circ Physiol. 2019 Nov 01;: Authors: Haushalter KJ, Schilling JM,...
Biology

mGluR5/ERK signaling regulated the phosphorylation and function of glycine receptor α1<sup>ins</sup> subunit in spinal dorsal horn of mice

Newsemia
by Zi-Yang Zhang, Hu-Hu Bai, Zhen Guo, Hu-Ling Li, Yong-Tao He, Xing-Lian Duan, Zhan-Wei Suo, Xian Yang, Yong-Xing He, Xiao-Dong Hu Inhibitory glycinergic transmission in...
Biology

Arabidopsis DGD1 SUPPRESSOR1 Is a Subunit of the Mitochondrial Contact Site and Cristae Organizing System and Affects Mitochondrial Biogenesis

Newsemia
Mitochondrial and plastid biogenesis requires the biosynthesis and assembly of proteins, nucleic acids, and lipids. In Arabidopsis (Arabidopsis thaliana), the mitochondrial outer membrane protein DGD1...
Biology

Transcriptional Repression of the APC/C Activator Genes CCS52A1/A2 by the Mediator Complex Subunit MED16 Controls Endoreduplication and Cell Growth in Arabidopsis

Newsemia
Endoreduplication, the replication of the nuclear genome in the absence of mitosis, is often associated with cell growth and differentiation in plants and animals, but...
Biology

Drosophila Mediator Subunit Med1 Is Required for GATA-Dependent Developmental Processes: Divergent Binding Interfaces for Conserved Coactivator Functions [Research Article]

Newsemia
DNA-bound transcription factors (TFs) governing developmental gene regulation have been proposed to recruit polymerase II machinery at gene promoters through specific interactions with dedicated subunits...
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GABAAR isoform and subunit structural motifs determine synaptic and extrasynaptic receptor localisation

Newsemia
Hannan, S; Minere, M; Harris, J; Izquierdo, P; Thomas, P; Tench, B; Smart, TG; (2019) GABAAR isoform and subunit structural motifs determine synaptic and extrasynaptic...

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