Tag: substrates

Pharma / Biotech

Electrochemical Vicinal Difluorination of Alkenes: Scalable, and Amenable to Electron-rich Substrates.

Newsemia
Related Articles Electrochemical Vicinal Difluorination of Alkenes: Scalable, and Amenable to Electron-rich Substrates. Angew Chem Int Ed Engl. 2019 Nov 07;: Authors: Doobary S, Sedikides...
Pharma / Biotech

Pharmacokinetic Drug-Drug Interactions Between Trospium Chloride and Ranitidine Substrates of Organic Cation Transporters in Healthy Human Subjects.

Newsemia
Related Articles Pharmacokinetic Drug-Drug Interactions Between Trospium Chloride and Ranitidine Substrates of Organic Cation Transporters in Healthy Human Subjects. J Clin Pharmacol. 2019 Sep 22;:...
Pharma / Biotech

Laparoscopic Roux-en-Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and CYP2E1 substrates.

Newsemia
Related Articles Laparoscopic Roux-en-Y gastric bypass surgery influenced pharmacokinetics of several drugs given as a cocktail with the highest impact observed for CYP1A2, CYP2C8 and...
Pharma / Biotech

ABCG2/BCRP: variants, transporter interaction profile of substrates and inhibitors.

Newsemia
Related Articles ABCG2/BCRP: variants, transporter interaction profile of substrates and inhibitors. Expert Opin Drug Metab Toxicol. 2019 Mar 11;: Authors: Safar Z, Kis E, Erdo...
Pharma / Biotech

Chemically reprogramming the phospho-transfer reaction to crosslink protein kinases to their substrates.

Newsemia
Related Articles Chemically reprogramming the phospho-transfer reaction to crosslink protein kinases to their substrates. Protein Sci. 2019 Jan 13;: Authors: Wong AW, Urisman A, Burlingame...
Pharma / Biotech

Gut microbiota-mediated bile acid transformations alter the cellular response to multidrug resistant transporter substrates in vitro: focus on P-glycoprotein.

Newsemia
Gut microbiota-mediated bile acid transformations alter the cellular response to multidrug resistant transporter substrates in vitro: focus on P-glycoprotein. Mol Pharm. 2018 Nov 02;: Authors:...

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