Tag : Substrate

Biology

Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1)

Newsemia
Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1) Source link...
Biology

MicroRNA 7 Impairs Insulin Signaling and Regulates A{beta} Levels through Posttranscriptional Regulation of the Insulin Receptor Substrate 2, Insulin Receptor, Insulin-Degrading Enzyme, and Liver X Receptor Pathway [Research Article]

Newsemia
Brain insulin resistance is a key pathological feature contributing to obesity, diabetes, and neurodegenerative disorders, including Alzheimer’s disease (AD). Besides the classic transcriptional mechanism mediated...
Latest News

Global $660Mn Sustained Release Coatings Market Outlook 2019-2024: Analyzed by Application, Substrate Type, Polymer Material Type, and Region – ResearchAndMarkets.com

Newsemia
DUBLIN–(BUSINESS WIRE)–The "Sustained Release Coatings Market by Application (In Vitro, In Vivo), Substrate Type, Polymer Material Type (Ethyl & Methyl Cellulose, Polyvinyl & Cellulose Acetate,...
Biology

Evolution of protein kinase substrate recognition at the active site

Newsemia
by David Bradley, Pedro Beltrao Protein kinases catalyse the phosphorylation of target proteins, controlling most cellular processes. The specificity of serine/threonine kinases is partly determined...
Pharma / Biotech

Secukinumab treatment does not alter the pharmacokinetics of the CYP3A4 substrate midazolam in patients with moderate to severe psoriasis.

Newsemia
Related Articles Secukinumab treatment does not alter the pharmacokinetics of the CYP3A4 substrate midazolam in patients with moderate to severe psoriasis. Clin Pharmacol Ther. 2019...
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An improved cell-permeable fluorogenic substrate as the basis for a highly sensitive test for NAD(P)H quinone oxidoreductase 1 (NQO1) in living cells

Newsemia
Cuff, S; Lewis, RD; Chinje, E; Jaffar, M; Knox, R; Weeks, I; (2018) An improved cell-permeable fluorogenic substrate as the basis for a highly sensitive...
Biology

Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

Newsemia
by Chad J. Miller, Hua Jane Lou, Craig Simpson, Bert van de Kooij, Byung Hak Ha, Oriana S. Fisher, Natasha L. Pirman, Titus J. Boggon,...
Pharma / Biotech

Effects of proton pump inhibitors, esomeprazole and vonoprazan, on the disposition of proguanil, a CYP2C19 substrate, in healthy volunteers.

Newsemia
Related Articles Effects of proton pump inhibitors, esomeprazole and vonoprazan, on the disposition of proguanil, a CYP2C19 substrate, in healthy volunteers. Br J Clin Pharmacol....
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Optical properties of beryllium-doped GaSb epilayers grown on GaAs substrate

Newsemia
Deng, Z; Chen, B; Chen, X; Shao, J; Gong, Q; Liu, H; Wu, J; (2018) Optical properties of beryllium-doped GaSb epilayers grown on GaAs substrate....

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