Tag : Steatohepatitis

Gastroenterology

Dipeptidyl peptidase-4 inhibitor protects against non-alcoholic steatohepatitis in mice by targeting TRAIL receptor-mediated lipoapoptosis via modulating hepatic dipeptidyl peptidase-4 expression

Newsemia
Dipeptidyl peptidase-4 inhibitor protects against non-alcoholic steatohepatitis in mice by targeting TRAIL receptor-mediated lipoapoptosis via modulating hepatic dipeptidyl peptidase-4 expression Source link...
Pharma / Biotech

Transporter activity changes in non-alcoholic steatohepatitis: assessment with plasma coproporphyrin I and III.

Newsemia
Related Articles Transporter activity changes in non-alcoholic steatohepatitis: assessment with plasma coproporphyrin I and III. J Pharmacol Exp Ther. 2020 Oct 30;: Authors: Chatterjee S,...
Gastroenterology

A composite biomarker using multiparametric magnetic resonance imaging and blood analytes accurately identifies patients with non-alcoholic steatohepatitis and significant fibrosis

Newsemia
A composite biomarker using multiparametric magnetic resonance imaging and blood analytes accurately identifies patients with non-alcoholic steatohepatitis and significant fibrosis Source link...
AI/ML

An Improved qFibrosis Algorithm for Precise Screening and Enrollment into Non-Alcoholic Steatohepatitis (NASH) Clinical Trials.

Newsemia
Related Articles An Improved qFibrosis Algorithm for Precise Screening and Enrollment into Non-Alcoholic Steatohepatitis (NASH) Clinical Trials. Diagnostics (Basel). 2020 Aug 28;10(9): Authors: Leow WQ,...
Cardiology

Non-alcoholic steatohepatitis and the risk of myocardial infarction: A population-based national study.

Newsemia
Related Articles Non-alcoholic steatohepatitis and the risk of myocardial infarction: A population-based national study. World J Hepatol. 2020 Jul 27;12(7):378-388 Authors: Ghoneim S, Dhorepatil A,...
Gastroenterology

Efficacy and Safety of Aldafermin, an Engineered FGF19 Analog, in a Randomized, Double-Blind, Placebo-Controlled Trial of Patients With Nonalcoholic Steatohepatitis

Newsemia
Aldafermin, an engineered analog of FGF19, inhibits bile acid synthesis and regulates metabolic homeostasis. We report results from a 24-week, phase 2 study, with serial...
Pharma / Biotech

Naringin ameliorates type 2 diabetes mellitus-induced steatohepatitis by inhibiting RAGE/NF-κB mediated mitochondrial apoptosis.

Newsemia
Related Articles Naringin ameliorates type 2 diabetes mellitus-induced steatohepatitis by inhibiting RAGE/NF-κB mediated mitochondrial apoptosis. Life Sci. 2020 Jul 20;:118118 Authors: Syed AA, Reza MI,...
Gastroenterology

Attribution of Nonalcoholic Steatohepatitis as an Etiology of Cirrhosis for Clinical Trials Eligibility: Recommendations from the Multi-stakeholder Liver ForumΩ

Newsemia
Attribution of Nonalcoholic Steatohepatitis as an Etiology of Cirrhosis for Clinical Trials Eligibility: Recommendations from the Multi-stakeholder Liver ForumΩ Source link...

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