Tag: splicing

AI/ML

Determination of RNA structural diversity and its role in HIV-1 RNA splicing.

Newsemia
Related Articles Determination of RNA structural diversity and its role in HIV-1 RNA splicing. Nature. 2020 Jun;582(7812):438-442 Authors: Tomezsko PJ, Corbin VDA, Gupta P, Swaminathan...
Biology

Phase separation of <i>Arabidopsis</i> EMB1579 controls transcription, mRNA splicing, and development

Newsemia
by Yiling Zhang, Zhankun Li, Naizhi Chen, Yao Huang, Shanjin Huang Tight regulation of gene transcription and mRNA splicing is essential for plant growth and...
Biology

An F-Box Protein, Mdm30, Interacts with TREX Subunit Sub2 To Regulate Cellular Abundance Cotranscriptionally in Orchestrating mRNA Export Independently of Splicing and Mitochondrial Function [Research Article]

Newsemia
Although an F-box protein, Mdm30, is found to regulate ubiquitylation of the Sub2 component of TREX (transcription-export) complex for proteasomal degradation in stimulation of mRNA...
Pediatrics

New Computational Tools Identify Alternative Splicing Changes in Aggressive Cancers

Newsemia
A multi-institutional group of researchers led by Children’s Hospital of Philadelphia (CHOP) has linked a strong cancer driver gene to changes in proteins that regulate...
Biology

Heterogeneous Nuclear Ribonucleoprotein H1 Coordinates with Phytochrome and the U1 snRNP Complex to Regulate Alternative Splicing in Physcomitrella patens

Newsemia
Plant photoreceptors tightly regulate gene expression to control photomorphogenic responses. Although gene expression is modulated by photoreceptors at various levels, the regulatory mechanism at the...
Biology

Evolution of intron splicing towards optimized gene expression is based on various <i>Cis</i>- and <i>Trans</i>-molecular mechanisms

Newsemia
by Idan Frumkin, Ido Yofe, Raz Bar-Ziv, Yonat Gurvich, Yen-Yun Lu, Yoav Voichek, Ruth Towers, Dvir Schirman, Heike Krebber, Yitzhak Pilpel Splicing expands, reshapes, and...

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