Tag : specificity

Biology

A Krüppel-like factor 1 (KLF1) Mutation Associated with Severe Congenital Dyserythropoietic Anemia Alters Its DNA-Binding Specificity [Research Article]

Newsemia
Krüppel-like factor 1 (KLF1/EKLF) is a transcription factor that globally activates genes involved in erythroid cell development. Various mutations are identified in the human KLF1...
Latest News

Sangamo Announces Nature Biotechnology Publication of New Strategies for Optimizing the Specificity of Gene Editing Nucleases

Newsemia
BRISBANE, Calif.–(BUSINESS WIRE)–Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, announced today the publication in Nature Biotechnology of a manuscript by Jeffrey Miller, Ph.D.,...
Biology

Analysis of Two New Arabinosyltransferases Belonging to the Carbohydrate-Active Enzyme (CAZY) Glycosyl Transferase Family1 Provides Insights into Disease Resistance and Sugar Donor Specificity

Newsemia
Glycosylation of small molecules is critical for numerous biological processes in plants, including hormone homeostasis, neutralization of xenobiotics, and synthesis and storage of specialized metabolites....
Pediatrics

Validation of the international Guide for Monitoring Child Development demonstrates good sensitivity and specificity in four diverse countries.

Newsemia
Related Articles Validation of the international Guide for Monitoring Child Development demonstrates good sensitivity and specificity in four diverse countries. Acta Paediatr. 2018 Nov 25;:...
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Raised VEGF: High sensitivity and specificity in the diagnosis of POEMS syndrome

Newsemia
Pihan, M; Keddie, S; D’Sa, S; Church, AJ; Yong, KL; Reilly, MM; Lunn, MP; (2018) Raised VEGF: High sensitivity and specificity in the diagnosis of...
AI/ML

De novo profile generation based on sequence context specificity with the long short-term memory network.

Newsemia
Related Articles De novo profile generation based on sequence context specificity with the long short-term memory network. BMC Bioinformatics. 2018 Jul 18;19(1):272 Authors: Yamada KD,...

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