Tag : solubility

Pharma / Biotech

Automatic Dissolution Testing with High-Temporal Resolution for Both Immediate-Release and Fixed-Combination Drug Tablets.

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Related Articles Automatic Dissolution Testing with High-Temporal Resolution for Both Immediate-Release and Fixed-Combination Drug Tablets. Sci Rep. 2019 11 19;9(1):17114 Authors: Chi Z, Azhar I,...
Pharma / Biotech

Spray-Drying, Solvent-Casting and Freeze-Drying Techniques: a Comparative Study on their Suitability for the Enhancement of Drug Dissolution Rates.

Newsemia
Related Articles Spray-Drying, Solvent-Casting and Freeze-Drying Techniques: a Comparative Study on their Suitability for the Enhancement of Drug Dissolution Rates. Pharm Res. 2020 Feb 19;37(3):57...
Pharma / Biotech

Relevance of control diet choice in metabolic studies: impact in glucose homeostasis and vascular function.

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Related Articles Relevance of control diet choice in metabolic studies: impact in glucose homeostasis and vascular function. Sci Rep. 2020 02 19;10(1):2902 Authors: González-Blázquez R,...
Pharma / Biotech

Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets.

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Related Articles Development of a dissolution method for lumefantrine and artemether in immediate release fixed dose artemether/lumefantrine tablets. Malar J. 2020 Apr 07;19(1):139 Authors: Belew...
Pharma / Biotech

Hypromellose acetate succinate based amorphous solid dispersions via hot melt extrusion: Effect of drug physicochemical properties.

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Related Articles Hypromellose acetate succinate based amorphous solid dispersions via hot melt extrusion: Effect of drug physicochemical properties. Carbohydr Polym. 2020 Apr 01;233:115828 Authors: Sarabu...
Pharma / Biotech

Synthesis, oral bioavailability evaluation and antiplatelet aggregation activity of three derivatives of 3,4‑dihydroxyacetophenone.

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Related Articles Synthesis, oral bioavailability evaluation and antiplatelet aggregation activity of three derivatives of 3,4‑dihydroxyacetophenone. Int J Mol Med. 2020 Mar;45(3):919-930 Authors: Sun N, Qu...
Pharma / Biotech

Solubility and Bioavailability Enhancement of Oridonin: A Review.

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Related Articles Solubility and Bioavailability Enhancement of Oridonin: A Review. Molecules. 2020 Jan 14;25(2): Authors: Zhang Y, Wang S, Dai M, Nai J, Zhu L,...
Pharma / Biotech

Surface stabilized atorvastatin nanocrystals with improved bioavailability, safety and antihyperlipidemic potential.

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Related Articles Surface stabilized atorvastatin nanocrystals with improved bioavailability, safety and antihyperlipidemic potential. Sci Rep. 2019 11 06;9(1):16105 Authors: Sharma M, Mehta I Abstract Atorvastatin,...
Pharma / Biotech

Phytosome-nanosuspensions for silybin-phospholipid complex with increased bioavailability and hepatoprotection efficacy.

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Related Articles Phytosome-nanosuspensions for silybin-phospholipid complex with increased bioavailability and hepatoprotection efficacy. Eur J Pharm Sci. 2020 Mar 01;144:105212 Authors: Chi C, Zhang C, Liu...
Pharma / Biotech

A Paclitaxel-Based Mucoadhesive Nanogel with Multivalent Interactions for Cervical Cancer Therapy.

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Related Articles A Paclitaxel-Based Mucoadhesive Nanogel with Multivalent Interactions for Cervical Cancer Therapy. Small. 2019 11;15(47):e1903208 Authors: Qian Q, Shi L, Gao X, Ma Y,...
Pharma / Biotech

Nanoparticle-mediated approaches for Alzheimer's disease pathogenesis, diagnosis, and therapeutics.

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Related Articles Nanoparticle-mediated approaches for Alzheimer’s disease pathogenesis, diagnosis, and therapeutics. J Control Release. 2019 11 28;314:125-140 Authors: Hettiarachchi SD, Zhou Y, Seven E, Lakshmana...
Pharma / Biotech

Biopharmaceutics and Pharmacokinetics of Timosaponin A-III by a Sensitive HPLC-MS/MS Method: Low Bioavailability Resulting from Poor Permeability and Solubility.

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Related Articles Biopharmaceutics and Pharmacokinetics of Timosaponin A-III by a Sensitive HPLC-MS/MS Method: Low Bioavailability Resulting from Poor Permeability and Solubility. Curr Pharm Biotechnol. 2020...
Biology

Fatty acid composition and N2 solubility in triacylglycerol-rich adipose tissue: the likely importance of intact molecular structure [RESEARCH ARTICLE]

Newsemia
Molly K. Gabler-Smith, Andrew J. Westgate, and Heather N. Koopman Diving tetrapods (sea turtles, seabirds and marine mammals) are a biologically diverse group, yet all...
Biology

Fatty acid composition and N2 solubility in triacylglycerol-rich adipose tissue: the likely importance of intact molecular structure [RESEARCH ARTICLE]

Newsemia
Molly K. Gabler-Smith, Andrew J. Westgate, and Heather N. Koopman Diving tetrapods (sea turtles, seabirds, marine mammals) are a biologically diverse group; yet, all are...
Pharma / Biotech

Prediction characteristics of oral absorption simulation software evaluated using structurally diverse low solubility drugs.

Newsemia
Related Articles Prediction characteristics of oral absorption simulation software evaluated using structurally diverse low solubility drugs. J Pharm Sci. 2019 Dec 18;: Authors: Matsumura N,...
Pharma / Biotech

A solid lipid nanoparticle formulation of 4-(N)-docosahexaenoyl 2', 2'-difluorodeoxycytidine with increased solubility, stability, and antitumor activity.

Newsemia
Related Articles A solid lipid nanoparticle formulation of 4-(N)-docosahexaenoyl 2′, 2′-difluorodeoxycytidine with increased solubility, stability, and antitumor activity. Int J Pharm. 2019 Aug 12;:118609 Authors:...
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The influence of drug solubility and sampling frequency on metformin and glibenclamide release from double-layered particles: experimental analysis and mathematical modelling

Newsemia
Shams, T; Brako, F; Huo, S; Harker, AH; Edirisinghe, U; Edirisinghe, M; (2019) The influence of drug solubility and sampling frequency on metformin and glibenclamide...

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