Tag : solid

Pharma / Biotech

Phase I study of CC-90010, a reversible, oral BET inhibitor in patients with advanced solid tumors and relapsed/refractory non-Hodgkin lymphoma.

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Related Articles Phase I study of CC-90010, a reversible, oral BET inhibitor in patients with advanced solid tumors and relapsed/refractory non-Hodgkin lymphoma. Ann Oncol. 2020...
Pharma / Biotech

Phase I study of Imalumab (BAX69), a Fully Human Recombinant Anti-oxidized Macrophage Migration Inhibitory Factor Antibody in Advanced Solid Tumors.

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Related Articles Phase I study of Imalumab (BAX69), a Fully Human Recombinant Anti-oxidized Macrophage Migration Inhibitory Factor Antibody in Advanced Solid Tumors. Br J Clin...
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KSQ Therapeutics Announces Discovery of Gene Targets with Potential Activity Superior to PD-1 for Development of Engineered Tumor Infiltrating Lymphocyte (eTIL™) Therapies for Solid Tumors

Newsemia
CAMBRIDGE, Mass.–(BUSINESS WIRE)–KSQ Therapeutics, a biotechnology company using its proprietary CRISPRomics® discovery platform to systematically screen the whole genome to identify optimal gene targets for...
Pharma / Biotech

A Phase I dose-escalation, pharmacokinetics and food-effect study of oral donafenib in patients with advanced solid tumours.

Newsemia
Related Articles A Phase I dose-escalation, pharmacokinetics and food-effect study of oral donafenib in patients with advanced solid tumours. Cancer Chemother Pharmacol. 2020 Feb 01;:...
Neurology

New approach can improve the activity of CAR-T cells against blood and solid cancers

Newsemia
A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in...
Biology

GPCRs show widespread differential mRNA expression and frequent mutation and copy number variation in solid tumors

Newsemia
by Krishna Sriram, Kevin Moyung, Ross Corriden, Hannah Carter, Paul A. Insel G protein-coupled receptors (GPCRs) are the most widely targeted gene family for Food...
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Mathematical modelling of coating film application onto pharmaceutical solid dosage forms

Newsemia
Christodoulou, Charalampos; (2019) Mathematical modelling of coating film application onto pharmaceutical solid dosage forms. Doctoral thesis (Ph.D), UCL (University College London). Source link...
Pharma / Biotech

A phase 1 study of the MDM2 antagonist RO6839921, a pegylated prodrug of idasanutlin, in patients with advanced solid tumors.

Newsemia
Related Articles A phase 1 study of the MDM2 antagonist RO6839921, a pegylated prodrug of idasanutlin, in patients with advanced solid tumors. Invest New Drugs....
Pharma / Biotech

Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial.

Newsemia
Related Articles Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial. Lancet Oncol. 2019...
Pharma / Biotech

Phase I trial of belinostat in combination with 13-cis-retinoic acid in advanced solid tumor malignancies: a California Cancer Consortium NCI/CTEP sponsored trial.

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Related Articles Phase I trial of belinostat in combination with 13-cis-retinoic acid in advanced solid tumor malignancies: a California Cancer Consortium NCI/CTEP sponsored trial. Cancer...
Pharma / Biotech

A solid lipid nanoparticle formulation of 4-(N)-docosahexaenoyl 2', 2'-difluorodeoxycytidine with increased solubility, stability, and antitumor activity.

Newsemia
Related Articles A solid lipid nanoparticle formulation of 4-(N)-docosahexaenoyl 2′, 2′-difluorodeoxycytidine with increased solubility, stability, and antitumor activity. Int J Pharm. 2019 Aug 12;:118609 Authors:...
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Stabilizing a high-voltage LiNi0.5Mn1.5O4 cathode towards all solid state batteries: a Li-Al-Ti-P-O solid electrolyte nano-shell with a host material

Newsemia
Li, L; Zhao, R; Xu, T; Wang, D; Pan, D; Zhang, K; Yu, C; … Bai, Y; + view all Li, L; Zhao, R; Xu,...

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