Tag : SOD1


Rational design of linear tripeptides against the aggregation of human mutant SOD1 protein causing amyotrophic lateral sclerosis

Formation of protein aggregation is considered a hallmark feature of various neurological diseases. Amyotrophic lateral sclerosis is one such devastating neurodegenerative disorder characterized by mutation...

Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS

by Fernanda A. Sala, Gareth S. A. Wright, Svetlana V. Antonyuk, Richard C. Garratt, S. Samar Hasnain Superoxide dismutase-1 (SOD1) maturation comprises a string of...

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