Tag : Simultaneous

Pharma / Biotech

HPLC-MS/MS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-β-d-glucuronide in human plasma.

Newsemia
Related Articles HPLC-MS/MS method for the simultaneous quantification of dolutegravir, elvitegravir, rilpivirine, darunavir, ritonavir, raltegravir and raltegravir-β-d-glucuronide in human plasma. J Pharm Biomed Anal. 2020...
Cardiology

En-Bloc Simultaneous Heart-Liver Transplantation in Adult Patients.

Newsemia
Related Articles En-Bloc Simultaneous Heart-Liver Transplantation in Adult Patients. Ann Surg. 2020 Jan 14;: Authors: Brozzi NA, Loebe M, Souki FG, Beduschi T, Ghodzisad A,...
Pharma / Biotech

Optimisation for simultaneous determination of iridoid glycosides and oligosaccharides in Radix Rehmannia by microwave assisted extraction and HILIC-UHPLC-TQ-MS/MS.

Newsemia
Related Articles Optimisation for simultaneous determination of iridoid glycosides and oligosaccharides in Radix Rehmannia by microwave assisted extraction and HILIC-UHPLC-TQ-MS/MS. Phytochem Anal. 2020 Jan 03;:...
Pharma / Biotech

Simultaneous quantification of ambrisentan, macitentan and sitaxentan in human plasma by using UPLC-MS/MS.

Newsemia
Related Articles Simultaneous quantification of ambrisentan, macitentan and sitaxentan in human plasma by using UPLC-MS/MS. Biomed Chromatogr. 2019 Dec 25;:e4787 Authors: van de Velde D,...
Pharma / Biotech

Simultaneous determination of eight bioactive constituents of Zhi-Zi-Hou-Po Decoction in rat plasma by ultra-high performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study.

Newsemia
Related Articles Simultaneous determination of eight bioactive constituents of Zhi-Zi-Hou-Po Decoction in rat plasma by ultra-high performance liquid chromatography with tandem mass spectrometry and its...
Biology

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation

Newsemia
by Cynthia J. Sakofsky, Natalie Saini, Leszek J. Klimczak, Kin Chan, Ewa P. Malc, Piotr A. Mieczkowski, Adam B. Burkholder, David Fargo, Dmitry A. Gordenin...
Pharma / Biotech

Simultaneous determination of four flavonoids in rat plasma after oral administration of Malus hupehensis (Pamp.) Rehd. extracts by UPLC-MS/MS and its application to a pharmacokinetics study.

Newsemia
Related Articles Simultaneous determination of four flavonoids in rat plasma after oral administration of Malus hupehensis (Pamp.) Rehd. extracts by UPLC-MS/MS and its application to...
Pharma / Biotech

Development and application of a rapid and sensitive LC-MS/MS method for simultaneous quantification of six diterpene lactones in rats after oral administration of Rhizoma Dioscoreae Bulbiferae extract.

Newsemia
Related Articles Development and application of a rapid and sensitive LC-MS/MS method for simultaneous quantification of six diterpene lactones in rats after oral administration of...
Pharma / Biotech

Simultaneous determination of multiple components in rat plasma and pharmacokinetic studies at a pharmacodynamic dose of Xian-Ling-Gu-Bao capsule by UPLC-MS/MS.

Newsemia
Related Articles Simultaneous determination of multiple components in rat plasma and pharmacokinetic studies at a pharmacodynamic dose of Xian-Ling-Gu-Bao capsule by UPLC-MS/MS. J Pharm Biomed...
Pharma / Biotech

Simultaneous analysis of the total plasma concentration of atorvastatin and its five metabolites and the unbound plasma concentration of atorvastatin: Application in a clinical pharmacokinetic study of single oral dose.

Newsemia
Related Articles Simultaneous analysis of the total plasma concentration of atorvastatin and its five metabolites and the unbound plasma concentration of atorvastatin: Application in a...
Pharma / Biotech

Simultaneous determination of five active alkaloids from Compound Kushen Injection in rat plasma by LC-MS/MS and its application to a comparative pharmacokinetic study in normal and NSCLC nude rats.

Newsemia
Related Articles Simultaneous determination of five active alkaloids from Compound Kushen Injection in rat plasma by LC-MS/MS and its application to a comparative pharmacokinetic study...
Pharma / Biotech

Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry.

Newsemia
Related Articles Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2019 Jul 16;176:112735...
Pharma / Biotech

Challenges in simultaneous extraction and chromatographic separation of metformin and three SGLT-2 inhibitors in human plasma using LC-MS/MS.

Newsemia
Related Articles Challenges in simultaneous extraction and chromatographic separation of metformin and three SGLT-2 inhibitors in human plasma using LC-MS/MS. J Pharm Biomed Anal. 2019...
Pediatrics

Potential for 'unpacking' complex simultaneous emotions in adolescence

Newsemia
Shows for the first time that complex, mixed simultaneous emotions in adolescents could be assessed using an Analogue Emotion Scale. Potential to supplement traditional emotional...
Pharma / Biotech

Simultaneous determination of eight constituents in rat plasma by HPLC-MS/MS and its application to a pharmacokinetic study after oral administration of Shejin-liyan Granule.

Newsemia
Simultaneous determination of eight constituents in rat plasma by HPLC-MS/MS and its application to a pharmacokinetic study after oral administration of Shejin-liyan Granule. Biomed Chromatogr....
Pharma / Biotech

Simultaneous determination of paclitaxel and lansoprazole in rat plasma by LC-MS/MS method and its application to a preclinical pharmacokinetic study of investigational PTX-LAN-PLGA nanoformulation.

Newsemia
Related Articles Simultaneous determination of paclitaxel and lansoprazole in rat plasma by LC-MS/MS method and its application to a preclinical pharmacokinetic study of investigational PTX-LAN-PLGA...
Pharma / Biotech

Development and validation of a chiral LC-ESI-MS/MS method for simultaneous determination of the enantiomeric metabolites isosorbide 2-mononitrate and isosorbide 5-mononitrate of isosorbide dinitrate in rat and human plasma.

Newsemia
Related Articles Development and validation of a chiral LC-ESI-MS/MS method for simultaneous determination of the enantiomeric metabolites isosorbide 2-mononitrate and isosorbide 5-mononitrate of isosorbide dinitrate...
Pharma / Biotech

UPLC/MS/MS assay for the simultaneous determination of seven antibiotics in human serum-Application to pediatric studies.

Newsemia
Related Articles UPLC/MS/MS assay for the simultaneous determination of seven antibiotics in human serum-Application to pediatric studies. J Pharm Biomed Anal. 2019 Mar 07;174:256-262 Authors:...
Pharma / Biotech

A simple, rapid and fully-validated HPLC method for simultaneous quantitative bio-analysis of Rosuvastatin and Candesartan in rat plasma: Application to pharmacokinetic interaction study.

Newsemia
A simple, rapid and fully-validated HPLC method for simultaneous quantitative bio-analysis of Rosuvastatin and Candesartan in rat plasma: Application to pharmacokinetic interaction study. Biomed Chromatogr....

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