Tag : Silencing

AI/ML

A robust model for quantitative prediction of the silencing efficacy of wild-type and A-to-I edited miRNAs.

Newsemia
Related Articles A robust model for quantitative prediction of the silencing efficacy of wild-type and A-to-I edited miRNAs. RNA Biol. 2020 02;17(2):264-280 Authors: Tian S,...
Latest News

Silencing Srsf6 does not modulate incomplete splicing of the huntingtin gene in Huntington's disease models

Newsemia
Mason, MA; Gomez-Paredes, C; Sathasivam, K; Neueder, A; Papadopoulou, A-S; Bates, GP; (2020) Silencing Srsf6 does not modulate incomplete splicing of the huntingtin gene in...
Latest News

Engineering Liposome-siRNA Vectors for Anti-Angiogenic Tumour Therapeutics by Gene Silencing

Newsemia
Podesta, Jennifer Elizabeth; (2010) Engineering Liposome-siRNA Vectors for Anti-Angiogenic Tumour Therapeutics by Gene Silencing. Doctoral thesis (Ph.D), UCL (University College London). Green open access Source...
Biology

Delineating the contribution of Spc105-bound PP1 to spindle checkpoint silencing and kinetochore microtubule attachment regulation

Newsemia
Accurate chromosome segregation during cell division requires the spindle assembly checkpoint (SAC), which detects unattached kinetochores, and an error correction mechanism that destabilizes incorrect kinetochore–microtubule...
Neurology

Silencing Novel Target Genes: A New Strategy for Lipid Lowering

Newsemia
Following in the footsteps of inclisiran, two lipid-lowering therapies based on silencing specific genes involved in lipid metabolism showed promising preliminary results in initial clinical...
Gastroenterology

DNA methylation silencing of microRNA gene methylator in the precancerous background mucosa with and without gastric cancer: Analysis of the effects of H. pylori eradication and long-term aspirin use

Newsemia
DNA methylation silencing of microRNA gene methylator in the precancerous background mucosa with and without gastric cancer: Analysis of the effects of H. pylori eradication...
Gastroenterology

Systematic gene silencing identified Cryptosporidium nucleoside diphosphate kinase and other molecules as targets for suppression of parasite proliferation in human intestinal cells

Newsemia
Systematic gene silencing identified Cryptosporidium nucleoside diphosphate kinase and other molecules as targets for suppression of parasite proliferation in human intestinal cells Source link...
Gastroenterology

Synergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia

Newsemia
Synergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia Source link...

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