Tag: Signal inhibition

Biology

High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning

Newsemia
by Mukul Tewary, Dominika Dziedzicka, Joel Ostblom, Laura Prochazka, Nika Shakiba, Tiam Heydari, Daniel Aguilar-Hidalgo, Curtis Woodford, Elia Piccinini, David Becerra-Alonso, Alice Vickers, Blaise Louis,...
Biology

The Hippo pathway integrates PI3K–Akt signals with mechanical and polarity cues to control tissue growth

Newsemia
by Nerea Borreguero-Muñoz, Georgina C. Fletcher, Mario Aguilar-Aragon, Ahmed Elbediwy, Zoé I. Vincent-Mistiaen, Barry J. Thompson The Hippo signalling pathway restricts cell proliferation in animal...
Biology

Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids

Newsemia
by Sapna Chhabra, Lizhong Liu, Ryan Goh, Xiangyu Kong, Aryeh Warmflash During gastrulation, the pluripotent epiblast self-organizes into the 3 germ layers—endoderm, mesoderm and ectoderm,...

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