Tag : Selectivity

Pharma / Biotech

Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability.

Newsemia
Related Articles Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability....
Biology

Single-cell selectivity and functional architecture of human lateral occipital complex

Newsemia
by Thomas Decramer, Elsie Premereur, Mats Uytterhoeven, Wim Van Paesschen, Johannes van Loon, Peter Janssen, Tom Theys The human lateral occipital complex (LOC) is more...
Biology

A temporal integration mechanism enhances frequency selectivity of broadband inputs to inferior colliculus

Newsemia
by Chen Chen, Heather L. Read, Monty A. Escabí Accurately resolving frequency components in sounds is essential for sound recognition, yet there is little direct...
Biology

Specific activation of pro-Infliximab enhances selectivity and safety of rheumatoid arthritis therapy

Newsemia
by Yun-Chi Lu, Chih-Hung Chuang, Kuo-Hsiang Chuang, I-Ju Chen, Bo-Cheng Huang, Wen-Han Lee, Hsin-Ell Wang, Jia-Je Li, Yi-An Cheng, Kai-Wen Cheng, Jaw-Yuan Wang, Yuan-Chin Hsieh,...
Cardiology

Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor.

Newsemia
Related Articles Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor. Neuropharmacology. 2019 Mar 02;: Authors: Bach A, Clausen BH, Kristensen LK,...
AI/ML

Differential Compound Prioritization via Bidirectional Selectivity Push with Power.

Newsemia
Related Articles Differential Compound Prioritization via Bidirectional Selectivity Push with Power. J Chem Inf Model. 2017 12 26;57(12):2958-2975 Authors: Liu J, Ning X Abstract Effective...

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