RNA

Long Noncoding RNA HOXA-AS3 Integrates NF-{kappa}B Signaling To Regulate Endothelium Inflammation [Research Article]

The long noncoding RNA HOXA-AS3 has recently been reported to act as a critical regulator in inflammation-linked lung adenocarcinoma. However, the roles of HOXA-AS3 in endothelium inflammation and related vascular...

Read more
Long noncoding RNA BFAL1 mediates enterotoxigenic Bacteroides fragilis-related carcinogenesis in colorectal cancer via the RHEB/mTOR pathway

Long noncoding RNA BFAL1 mediates enterotoxigenic Bacteroides fragilis-related carcinogenesis in colorectal cancer via the RHEB/mTOR pathway Source link

Read more
CRISPR-Cas9 successfully reverses type 2 diabetes in mice

Researchers have used CRISPR-Cas9 to treat obesity and type 2 diabetes in mice, a development that could eventually benefit humans. Source link

Read more
Mount Sinai researchers discover drug resistance signature in Crohn's disease

By mapping out more than 100,000 immune cells in patients with Crohn's disease, Mount Sinai researchers have discovered a signature of cells that are involved in a type of the...

Read more
Study shows microRNA can protect the heart from reperfusion injury

Heart muscle can continue to die even after restoring blood following a heart attack, and scientists have new evidence that one way to help it live is by boosting levels...

Read more
The hunt for RNA polymerase II elongation factors: a historical perspective

The hunt for RNA polymerase II elongation factors: a historical perspective Source link

Read more
Researchers explain how diabetes increases cancer risk

For years, scientists have been trying to solve a medical mystery: Why do people with type 1 or type 2 diabetes have an increased risk of developing some forms of...

Read more
RNA sequencing data added to robust study of Parkinson's disease

A team at the Keck School of Medicine of USC, in collaboration with The Michael J. Fox Foundation for Parkinson's Research, has just added a crucial new element - RNA...

Read more
Post-Doc Position: Alternative-Splicing and RNA isoform expression in Wnt signalling

We are looking for an RNA molecular biologist/molecular developmental biologist (three years, BBSRC funded, currently proposed start date 1 January 2020, mostly based in Aberdeen) (apply by 26 August 2019)...

Read more
Circular RNA profile identifies circOSBPL10 as an oncogenic factor and prognostic marker in gastric cancer

Circular RNA profile identifies circOSBPL10 as an oncogenic factor and prognostic marker in gastric cancer Source link

Read more
Long non-coding RNA KRT19P3 suppresses proliferation and metastasis through COPS7A-mediated NF-κB pathway in gastric cancer

Long non-coding RNA KRT19P3 suppresses proliferation and metastasis through COPS7A-mediated NF-κB pathway in gastric cancer Source link

Read more
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation

A defining feature of embryonic stem cells (ESCs) is the ability to differentiate into all three germ layers. Pluripotency is maintained in part by a unique transcription network that maintains...

Read more
Breakthrough study identifies specific antibody target implicated in neuropsychiatric lupus

A breakthrough study by a SUNY Downstate Health Sciences University research team has identified a specific antibody target implicated in neuropsychiatric symptoms of lupus. Source link

Read more
Study reveals surprising discoveries about poorly understood glioblastoma

Glioblastoma, a cancer that arises in the brain's supporting glial cells, is one of the worst diagnoses a child can receive. The grade IV, highly malignant tumor aggressively infiltrates healthy...

Read more
A precision RNA degradation machinery shapes stem cell development

In this issue, Belair et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201811148) show that, together with a complex network of transcription factors and chromatin modifiers, the RNA exosome regulates embryonic stem...

Read more
DSP1 and DSP4 Act Synergistically in Small Nuclear RNA 3' End Maturation and Pollen Growth

Small nuclear RNAs (snRNAs) play essential roles in spliceosome assembly and splicing. Most snRNAs are transcribed by the DNA-dependent RNA polymerase II (Pol II) and require 3'-end endonucleolytic cleavage. We...

Read more
Designer PPR Proteins as Tools to Explore RNA Binding in Vivo

Designer PPR Proteins as Tools to Explore RNA Binding in Vivo Source link

Read more
Moffitt study uncovers subtypes of squamous cell lung cancer

Lung cancer is the number one cause of cancer-related deaths in the United States, with squamous cell lung cancer (SCC) being one of the common types. Source link

Read more
Father Knows Best? Small RNA Pathway Controls Endosperm Response to Paternal Genomic Dosage

Father Knows Best? Small RNA Pathway Controls Endosperm Response to Paternal Genomic Dosage Source link

Read more
Characterization of a long noncoding RNA Pcdh17it as a novel marker for immature premyelinating oligodendrocytes

Kasuga, Y; Fudge, AD; Zhang, Y; Li, H; (2019) Characterization of a long noncoding RNA Pcdh17it as a novel marker for immature premyelinating oligodendrocytes. Glia 10.1002/glia.23684 . (In press). Source...

Read more