RNA – Newsemia

SARS-CoV-2 detected in Santiago, Chile wastewater with very little loss of viral RNA

NewsemiaJuly 7, 2020

by NewsemiaJuly 7, 202000

A preliminary report from Chile describes the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in sewage as a sensitive method to assess the...

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Research suggests protective effect of influenza vaccine against COVID-19 severity and mortality

NewsemiaJuly 6, 2020

by NewsemiaJuly 6, 202000

A new study involving over 92,000 patients with COVID-19 in Brazil shows that the odds of severe disease, ventilatory support requirement, and death are reduced...

Neurology

C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression

NewsemiaJuly 3, 2020

by NewsemiaJuly 3, 202000

C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression Source link...

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New platform prioritizes synergistic drug combinations against SARS-CoV-2

NewsemiaJuly 2, 2020

by NewsemiaJuly 2, 202000

Researchers in the U.S. have used a new web-based platform to help identify synergistic and antagonistic drug combinations and their underlying mechanisms of action in...

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Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

NewsemiaJuly 2, 2020

by NewsemiaJuly 2, 202000

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development. Source link...

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Long-term endurance training alters the activity of genes involved in metabolic health

NewsemiaJune 23, 2020

by NewsemiaJune 23, 202000

Decades-long endurance training alters the activity of genes in human skeletal muscle that are important for metabolic health. Source link...

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Single-dose Israeli vaccine candidate protective against SARS-CoV-2

NewsemiaJune 23, 2020

by NewsemiaJune 23, 202000

Now, a new Israeli study published on the preprint server bioRxiv in June 2020 reports a new recombinant vaccine expressing the S or spike protein...

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SARS-CoV-2 saliva testing that omits the RNA extraction step

NewsemiaJune 22, 2020

by NewsemiaJune 22, 202000

Even as the COVID-19 pandemic progresses throughout the world, the lack of consistent diagnostic testing has been a bugbear, preventing public health control of the...

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Environmental conditions affect the stability of SARS-CoV-2, study finds

NewsemiaJune 21, 2020

by NewsemiaJune 21, 202000

A new study led by Marshall University researcher M. Jeremiah Matson found that environmental conditions affect the stability of the severe acute respiratory syndrome coronavirus...

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Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

NewsemiaJune 21, 2020

by NewsemiaJune 21, 202000

Aging is the main risk factor for dementia and Parkinson’s disease. As age progresses, toxic protein aggregates pile up in the brain and impair neuronal...

Biology

Molecular Topology of RNA Polymerase I Upstream Activation Factor [Research Article]

NewsemiaJune 19, 2020

by NewsemiaJune 19, 202000

Upstream activation factor (UAF) is a multifunctional transcription factor in Saccharomyces cerevisiae that plays dual roles in activating RNA polymerase I (Pol I) transcription and...

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Using stem cells to study the developmental effects of Neandertal DNA

NewsemiaJune 19, 2020

by NewsemiaJune 19, 202000

Protocols that allow the transformation of human induced pluripotent stem cell (iPSC) lines into organoids have changed the way scientists can study developmental processes and...

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New test can detect the RNA of SARS-CoV-2 in patient samples in 30 minutes

NewsemiaJune 14, 2020

by NewsemiaJune 14, 2020016

A new diagnostic test can detect the RNA of SARS-CoV-2, the virus that causes COVID-19, in urine, blood, saliva or mouth swab samples in just...

Gastroenterology

SARS-CoV-2 RNA Detection in Gastrointestinal Sample Displays Poor Performance

NewsemiaJune 14, 2020

by NewsemiaJune 14, 2020021

SARS-CoV-2 RNA Detection in Gastrointestinal Sample Displays Poor Performance Source link...

Biology

A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

NewsemiaJune 10, 2020

by NewsemiaJune 10, 2020020

by Eric J. Snijder, Ronald W. A. L. Limpens, Adriaan H. de Wilde, Anja W. M. de Jong, Jessika C. Zevenhoven-Dobbe, Helena J. Maier, Frank...

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GMU researchers studying effect of cannabidiol on exosome release

NewsemiaJune 7, 2020

by NewsemiaJune 7, 202003

Fatah Kashanchi, Professor, Laboratory of Molecular Virology, School of Systems Biology, and Lance Liotta, Co-Director, Applied Proteomics and Molecular Medicine, are working to mitigate virally...

Biology

Characterization of Arabidopsis thaliana Promoter Bidirectionality and Antisense RNAs by Inactivation of Nuclear RNA Decay Pathways

NewsemiaJune 6, 2020

by NewsemiaJune 6, 2020024

In animals, RNA polymerase II initiates transcription bidirectionally from gene promoters to produce pre-mRNAs on the forward strand and promoter upstream transcripts (PROMPTs) on the...

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Genetron Health Receives FDA Emergency Use Authorization for SARS-CoV-2 RNA Test and Approval for Export by Chinese Authority

NewsemiaJune 6, 2020

by NewsemiaJune 6, 2020020

BEIJING–(BUSINESS WIRE)–Genetron Holdings Limited (“Genetron Health”), a China-based precision oncology company that covers full-cycle cancer care, announced that its independently developed detection kit for the...

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SARS-CoV-2 gene deletions may cause milder infections and increase human-to-human transmission

NewsemiaJune 5, 2020

by NewsemiaJune 5, 202001

In their recent paper released on the bioRxiv preprint server, a research group from Spain demonstrated how genome changes and deletions in severe acute respiratory...

Neurology

How COVID-19 affects the nervous system

NewsemiaJune 1, 2020

by NewsemiaJune 1, 202002

A new paper published in the journal JAMA Neurology in May 2020 discusses the presentation and complications of COVID-19 with respect to the nervous system....