Tag : RNA sequencing

Biology

SCRINSHOT enables spatial mapping of cell states in tissue sections with single-cell resolution

Newsemia
by Alexandros Sountoulidis, Andreas Liontos, Hong Phuong Nguyen, Alexandra B. Firsova, Athanasios Fysikopoulos, Xiaoyan Qian, Werner Seeger, Erik Sundström, Mats Nilsson, Christos Samakovlis Changes in...
Dermatology

Computational method could predict immunotherapy response in patients with advanced melanoma

Newsemia
A computational method that combines clinicodemographic variables with deep learning of pre-treatment histology images could predict response to immune checkpoint blockade among patients with advanced...
Biology

The noncoding small RNA SsrA is released by <i>Vibrio fischeri </i>and modulates critical host responses

Newsemia
by Silvia Moriano-Gutierrez, Clotilde Bongrand, Tara Essock-Burns, Leo Wu, Margaret J. McFall-Ngai, Edward G. Ruby The regulatory noncoding small RNAs (sRNAs) of bacteria are key...
Biology

Interphase-arrested <i>Drosophila</i> embryos activate zygotic gene expression and initiate mid-blastula transition events at a low nuclear-cytoplasmic ratio

Newsemia
by Isaac J. T. Strong, Xiaoyun Lei, Fang Chen, Kai Yuan, Patrick H. O’Farrell Externally deposited eggs begin development with an immense cytoplasm and a...
Gastroenterology

Multimodal mapping of immune landscape in pancreatic cancer could guide personalized therapies

Newsemia
Stubbornly, frustratingly, pancreatic cancer has remained resistant to immunotherapies that are revolutionizing the treatment of many types of cancer. Source link...
Biology

High-throughput mapping of the phage resistance landscape in <i>E</i>. <i>coli</i>

Newsemia
by Vivek K. Mutalik, Benjamin A. Adler, Harneet S. Rishi, Denish Piya, Crystal Zhong, Britt Koskella, Elizabeth M. Kutter, Richard Calendar, Pavel S. Novichkov, Morgan...
Biology

Centrioles are amplified in cycling progenitors of olfactory sensory neurons

Newsemia
by Kaitlin Ching, Tim Stearns Olfaction in most animals is mediated by neurons bearing cilia that are accessible to the environment. Olfactory sensory neurons (OSNs)...
Latest News

Central nervous system immune responses to COVID-19

Newsemia
A recent study published on the preprint server bioRxiv by scientists from Yale School of Medicine, University of California, Yale School of Public Health, Yale...
Latest News

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Newsemia
As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person. Source...
Biology

The pregnant myometrium is epigenetically activated at contractility-driving gene loci prior to the onset of labor in mice

Newsemia
by Virlana M. Shchuka, Luis E. Abatti, Huayun Hou, Nawrah Khader, Anna Dorogin, Michael D. Wilson, Oksana Shynlova, Jennifer A. Mitchell During gestation, uterine smooth...
Biology

IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival

Newsemia
by Alyssa Batista, Jeffrey J. Rodvold, Su Xian, Stephen C. Searles, Alyssa Lew, Takao Iwawaki, Gonzalo Almanza, T. Cameron Waller, Jonathan Lin, Kristen Jepsen, Hannah...
Pediatrics

New Tool Improves Ability to Gather Useful Genetic Information Obtained from Blood and Skin Tissues

Newsemia
Hoping to refine the usefulness of RNA sequencing, a team of researchers reviewed a database of RNA sequencing results in non-clinically-accessible tissues from organs like...
Biology

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes

Newsemia
by Noriki Fujimoto, Yuliang He, Marco D’Addio, Carlotta Tacconi, Michael Detmar, Lothar C. Dieterich Lymph nodes (LNs) are highly organized secondary lymphoid organs that mediate...
Biology

Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize

Newsemia
by Yalin Liu, Handong Su, Jing Zhang, Yang Liu, Chao Feng, Fangpu Han In most plants, centromeric DNA contains highly repetitive sequences, including tandem repeats...
Latest News

MIT researchers develop method to isolate T cells primed for certain allergies or infections

Newsemia
When your immune system is exposed to a vaccine, an allergen, or an infectious microbe, subsets of T cells that can recognize a foreign intruder...

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