Tag: RNA sequencing

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Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Newsemia
As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person. Source...
Biology

The pregnant myometrium is epigenetically activated at contractility-driving gene loci prior to the onset of labor in mice

Newsemia
by Virlana M. Shchuka, Luis E. Abatti, Huayun Hou, Nawrah Khader, Anna Dorogin, Michael D. Wilson, Oksana Shynlova, Jennifer A. Mitchell During gestation, uterine smooth...
Biology

IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival

Newsemia
by Alyssa Batista, Jeffrey J. Rodvold, Su Xian, Stephen C. Searles, Alyssa Lew, Takao Iwawaki, Gonzalo Almanza, T. Cameron Waller, Jonathan Lin, Kristen Jepsen, Hannah...
Pediatrics

New Tool Improves Ability to Gather Useful Genetic Information Obtained from Blood and Skin Tissues

Newsemia
Hoping to refine the usefulness of RNA sequencing, a team of researchers reviewed a database of RNA sequencing results in non-clinically-accessible tissues from organs like...
Biology

Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes

Newsemia
by Noriki Fujimoto, Yuliang He, Marco D’Addio, Carlotta Tacconi, Michael Detmar, Lothar C. Dieterich Lymph nodes (LNs) are highly organized secondary lymphoid organs that mediate...
Biology

Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize

Newsemia
by Yalin Liu, Handong Su, Jing Zhang, Yang Liu, Chao Feng, Fangpu Han In most plants, centromeric DNA contains highly repetitive sequences, including tandem repeats...
Latest News

MIT researchers develop method to isolate T cells primed for certain allergies or infections

Newsemia
When your immune system is exposed to a vaccine, an allergen, or an infectious microbe, subsets of T cells that can recognize a foreign intruder...
Biology

Recurrent functional misinterpretation of RNA-seq data caused by sample-specific gene length bias

Newsemia
by Shir Mandelboum, Zohar Manber, Orna Elroy-Stein, Ran Elkon Data normalization is a critical step in RNA sequencing (RNA-seq) analysis, aiming to remove systematic effects...
Gastroenterology

Mount Sinai researchers discover drug resistance signature in Crohn's disease

Newsemia
By mapping out more than 100,000 immune cells in patients with Crohn’s disease, Mount Sinai researchers have discovered a signature of cells that are involved...
Biology

Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

Newsemia
by Lech Kaczmarczyk, Vikas Bansal, Ashish Rajput, Raza-ur Rahman, Wiesław Krzyżak, Joachim Degen, Stefanie Poll, Martin Fuhrmann, Stefan Bonn, Walker Scot Jackson A deep understanding...
Latest News

Study maps bone marrow niche populations and their differentiation paths

Newsemia
Bone marrow contains biological factories, which pump out billions of new blood cells daily. The non-blood cells that maintain this production also have the potential...
Biology

Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

Newsemia
by Oliver Smith, Glenn Dunshea, Mikkel-Holger S. Sinding, Sergey Fedorov, Mietje Germonpre, Hervé Bocherens, M. T. P. Gilbert While sequencing ancient DNA (aDNA) from archaeological...
Latest News

Researchers use artificial intelligence to predict molecular classification of colorectal cancer

Newsemia
Treating physicians need information about the molecular subtype of the tumor if they are to provide targeted therapy for colorectal carcinoma. Source link...

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