Tag : Ribosomes

Biology

A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool

Newsemia
by Melissa D. Parker, Jason C. Collins, Boguslawa Korona, Homa Ghalei, Katrin Karbstein Premature release of nascent ribosomes into the translating pool must be prevented...
Biology

Inverted translational control of eukaryotic gene expression by ribosome collisions

Newsemia
by Heungwon Park, Arvind R. Subramaniam The canonical model of eukaryotic translation posits that efficient translation initiation increases protein expression and mRNA stability. Contrary to...
Biology

Single-molecule correlated chemical probing reveals large-scale structural communication in the ribosome and the mechanism of the antibiotic spectinomycin in living cells

Newsemia
by Arnab Sengupta, Greggory M. Rice, Kevin M. Weeks The ribosome moves between distinct structural states and is organized into multiple functional domains. Here, we...
Biology

Tagger—A Swiss army knife for multiomics to dissect cell type–specific mechanisms of gene expression in mice

Newsemia
by Lech Kaczmarczyk, Vikas Bansal, Ashish Rajput, Raza-ur Rahman, Wiesław Krzyżak, Joachim Degen, Stefanie Poll, Martin Fuhrmann, Stefan Bonn, Walker Scot Jackson A deep understanding...
Latest News

Researchers discover new function of ribosomes in human cells

Newsemia
Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle’s role...
Biology

Lso2 is a conserved ribosome-bound protein required for translational recovery in yeast

Newsemia
by Yinuo J. Wang, Pavanapuresan P. Vaidyanathan, Maria F. Rojas-Duran, Namrata D. Udeshi, Kristen M. Bartoli, Steven A. Carr, Wendy V. Gilbert Ribosome-binding proteins function...
Biology

Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during <i>Drosophila</i> development

Newsemia
by Hong Zhang, Shengqian Dou, Feng He, Junjie Luo, Liping Wei, Jian Lu Upstream open reading frames (uORFs) play important roles in regulating the main...

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