Tag : ribosomal RNA

Biology

A kinase-dependent checkpoint prevents escape of immature ribosomes into the translating pool

Newsemia
by Melissa D. Parker, Jason C. Collins, Boguslawa Korona, Homa Ghalei, Katrin Karbstein Premature release of nascent ribosomes into the translating pool must be prevented...
Biology

Single-molecule correlated chemical probing reveals large-scale structural communication in the ribosome and the mechanism of the antibiotic spectinomycin in living cells

Newsemia
by Arnab Sengupta, Greggory M. Rice, Kevin M. Weeks The ribosome moves between distinct structural states and is organized into multiple functional domains. Here, we...
Biology

Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival

Newsemia
by Oliver Smith, Glenn Dunshea, Mikkel-Holger S. Sinding, Sergey Fedorov, Mietje Germonpre, Hervé Bocherens, M. T. P. Gilbert While sequencing ancient DNA (aDNA) from archaeological...
Biology

Lso2 is a conserved ribosome-bound protein required for translational recovery in yeast

Newsemia
by Yinuo J. Wang, Pavanapuresan P. Vaidyanathan, Maria F. Rojas-Duran, Namrata D. Udeshi, Kristen M. Bartoli, Steven A. Carr, Wendy V. Gilbert Ribosome-binding proteins function...
Biology

<i>Drosophila melanogaster</i> establishes a species-specific mutualistic interaction with stable gut-colonizing bacteria

Newsemia
by Inês S. Pais, Rita S. Valente, Marta Sporniak, Luis Teixeira Animals live together with diverse bacteria that can impact their biology. In Drosophila melanogaster,...
AI/ML

Benchmarking differential expression analysis tools for RNA-Seq: normalization-based vs. log-ratio transformation-based methods

Newsemia
Count data generated by next-generation sequencing assays do not measure absolute transcript abundances. Instead, the data are constrained to an arbitrary “library size” by the...

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