Tag: repurposing

AI/ML

Synergistic drug combinations and machine learning for drug repurposing in chordoma.

Newsemia
Related Articles Synergistic drug combinations and machine learning for drug repurposing in chordoma. Sci Rep. 2020 Jul 31;10(1):12982 Authors: Anderson E, Havener TM, Zorn KM,...
Cardiology

The rationale for repurposing funny current inhibition for management of ventricular arrhythmia.

Newsemia
The rationale for repurposing funny current inhibition for management of ventricular arrhythmia. Heart Rhythm. 2020 Jul 29;: Authors: Chakraborty P, Rose RA, Nair K, Downar...
Biology

Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of <i>Trypanosoma brucei</i>

Newsemia
by Eva Doleželová, Michaela Kunzová, Mario Dejung, Michal Levin, Brian Panicucci, Clément Regnault, Christian J. Janzen, Michael P. Barrett, Falk Butter, Alena Zíková Mitochondrial metabolic...
Pharma / Biotech

Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics.

Newsemia
Prioritisation of Anti-SARS-Cov-2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics. Clin Pharmacol Ther. 2020 May 21;:...
Latest News

Repurposing anti-diabetic drugs for the treatment of Parkinson's disease: Rationale and clinical experience

Newsemia
Foltynie, T; Athauda, D; (2020) Repurposing anti-diabetic drugs for the treatment of Parkinson’s disease: Rationale and clinical experience. Progress in Brain Research , 252 pp....
Latest News

Cost of ‘repurposing’ existing drugs to treat COVID-19

Newsemia
The paper looks at repurposed drugs that might demonstrate efficacy against COVID-19, and if they could be manufactured profitably at very low costs to ensure...
Pharma / Biotech

The first wide-scale drug repurposing screen using the Prestwick Chemical Library (1200 bioactive molecules) against Neisseria gonorrhoeae identifies high in vitro activity of auranofin and many additional drugs.

Newsemia
Related Articles The first wide-scale drug repurposing screen using the Prestwick Chemical Library (1200 bioactive molecules) against Neisseria gonorrhoeae identifies high in vitro activity of...
Neurology

Repurposing azithromycin for neonatal neuroprotection.

Newsemia
Related Articles Repurposing azithromycin for neonatal neuroprotection. Pediatr Res. 2019 May 17;: Authors: Barks JDE, Liu Y, Wang L, Pai MP, Silverstein FS Abstract BACKGROUND:...

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