Tag : rational

Pharma / Biotech

Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses.

Newsemia
Related Articles Rational design of adjuvants for subunit vaccines: The format of cationic adjuvants affects the induction of antigen-specific antibody responses. J Control Release. 2020...
Biology

Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C

Newsemia
by Lisa Bauer, Roberto Manganaro, Birgit Zonsics, Daniel L. Hurdiss, Marleen Zwaagstra, Tim Donselaar, Naemi G. E. Welter, Regina G. D. M. van Kleef, Moira...
Latest News

L’Institute for Rational Drug Policies et le Parti pirate européen demandent à la Commission européenne de mettre en œuvre des politiques de réduction des risques afin d’aider les citoyens européens à faire des choix de vie positifs

Newsemia
BRUXELLES–(BUSINESS WIRE)–Un webinaire sur la prévention des maladies axée sur les citoyens, organisé par l’Institute for Rational Drug Policies (IRAP) en coopération avec les Pirates...
Biology

Rational design of balanced dual-targeting antibiotics with limited resistance

Newsemia
by Akos Nyerges, Tihomir Tomašič, Martina Durcik, Tamas Revesz, Petra Szili, Gabor Draskovits, Ferenc Bogar, Žiga Skok, Nace Zidar, Janez Ilaš, Anamarija Zega, Danijel Kikelj,...
Dentistry

Phototherapy as a Rational Antioxidant Treatment Modality in COVID-19 Management; New Concept and Strategic Approach: Critical Review.

Newsemia
Related Articles Phototherapy as a Rational Antioxidant Treatment Modality in COVID-19 Management; New Concept and Strategic Approach: Critical Review. Antioxidants (Basel). 2020 Sep 16;9(9): Authors:...
AI/ML

Biosynthetic Short Neuropeptides: A Rational Theory Based on Experimental Results for the Missing Pain-Relief Opioid Endomorphin Precursor Gene.

Newsemia
Related Articles Biosynthetic Short Neuropeptides: A Rational Theory Based on Experimental Results for the Missing Pain-Relief Opioid Endomorphin Precursor Gene. Chembiochem. 2019 08 16;20(16):2054-2058 Authors:...
Latest News

Rational immobilisation of enzymes: Immobilisation of transketolase for carbon-carbon bond synthesis.

Newsemia
Brocklebank, Simon Pearson; (1999) Rational immobilisation of enzymes: Immobilisation of transketolase for carbon-carbon bond synthesis. Doctoral thesis (Ph.D.), University College London. Green open access Source...
Dentistry

Managing Acute Dental Pain: Principles for Rational Prescribing and Alternatives to Opioid Therapy.

Newsemia
Managing Acute Dental Pain: Principles for Rational Prescribing and Alternatives to Opioid Therapy. Dent Clin North Am. 2020 Jul;64(3):525-534 Authors: Khawaja SN, Scrivani SJ Abstract...
Pharma / Biotech

A Rational Use of Clozapine Based on Adverse Drug Reactions, Pharmacokinetics, and Clinical Pharmacopsychology.

Newsemia
Related Articles A Rational Use of Clozapine Based on Adverse Drug Reactions, Pharmacokinetics, and Clinical Pharmacopsychology. Psychother Psychosom. 2020 Apr 14;:1-15 Authors: de Leon J,...
Neurology

Rational design of linear tripeptides against the aggregation of human mutant SOD1 protein causing amyotrophic lateral sclerosis

Newsemia
Formation of protein aggregation is considered a hallmark feature of various neurological diseases. Amyotrophic lateral sclerosis is one such devastating neurodegenerative disorder characterized by mutation...
Pharma / Biotech

Novel phenanthridin-6(5H)-one derivatives as potent and selective BET bromodomain inhibitors: Rational design, synthesis and biological evaluation.

Newsemia
Related Articles Novel phenanthridin-6(5H)-one derivatives as potent and selective BET bromodomain inhibitors: Rational design, synthesis and biological evaluation. Eur J Med Chem. 2019 Jun 28;179:502-514...
Cardiology

Rational and design of the INtentional COronary revascularization versus conservative therapy in patients undergOing successful peripheRAl arTEry revascularization due to critical limb ischemia trial (INCORPORATE trial).

Newsemia
Related Articles Rational and design of the INtentional COronary revascularization versus conservative therapy in patients undergOing successful peripheRAl arTEry revascularization due to critical limb ischemia...
Biology

Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors

Newsemia
by Lei Cao, Pi Liu, Pan Yang, Qiang Gao, Hong Li, Yao Sun, Ling Zhu, Jianping Lin, Dan Su, Zihe Rao, Xiangxi Wang Hepatitis A...

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