Tag : protein

Cardiology

Distinct regulation of cardiac fibroblast proliferation and transdifferentiation by classical and novel protein kinase C isoforms: possible implications for new antifibrotic therapies.

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Related Articles Distinct regulation of cardiac fibroblast proliferation and transdifferentiation by classical and novel protein kinase C isoforms: possible implications for new antifibrotic therapies. Mol...
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Researchers study the role of viral intramebrane interactions in controlling programmed cell death

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A research group from the Department of Biochemistry and Molecular Biology of the University of Valencia (UV), in coordination with the National Centre for Biotechnology...
AI/ML

PTMsnp: A Web Server for the Identification of Driver Mutations That Affect Protein Post-translational Modification.

Newsemia
Related Articles PTMsnp: A Web Server for the Identification of Driver Mutations That Affect Protein Post-translational Modification. Front Cell Dev Biol. 2020;8:593661 Authors: Peng D,...
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SARS-CoV-2 launches multipronged attack against host cell protein synthesis, study finds

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An interesting new study throws a flood of light on how SARS-CoV-2 accomplishes its mission to infect and replicate within host cells while evading the...
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SARS-CoV-2 spike protein shows slow but stable evolution, study finds

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A new preprint published in November 2020 describes the seven different clades into which the virus has diversified. Source link...
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Monoclonal antibody HB27 shows potent neutralizing activity against SARS-CoV-2

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A new study reports a very promising anti-SARS-CoV-2 monoclonal antibody, HB27, that appears to have two distinct mechanisms of action inhibiting the virus-host cell interaction...
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N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

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Researchers from the Harbin Institute of Technology, China, modeled the complexes formed between the RBD and the human ACE2 and monoclonal antibodies. Source link...
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Siemens Healthineers SARS-CoV-2 IgG antibody test demonstrates ability to detect neutralizing antibodies

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Siemens Healthineers has announced its SARS-CoV-2 IgG Antibody Test has proven to measure neutralizing antibodies and has achieved CE Mark. The test is an enhanced...
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Researchers develop synthetic defective SARS-CoV-2 genome that inhibits viral replication

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A shorter genome comprising only a part of the SARS-CoV-2’s RNA genome competes with the normal virus for growth and can potentially prevent viral replication....
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Phycobilins found to inhibit SARS-CoV-2 enzymes in vitro

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Researchers have released an interesting new study that describes the broad-spectrum of antiviral activity that phycobilins can have. Phycobilins, which are bioactive plant compounds, were...
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Early interferon therapy may mitigate COVID-19 severity

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A recent review of COVID-19 therapies explores the utility of interferons in the battle against severe COVID-19, and concludes that they deserve further development. Source...
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Inhibiting SARS-CoV-2 cell entry with monoclonal antibodies against staphylococcal enterotoxin B superantigen

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In a recent cutting-edge study, US researchers unveiled an anti-staphylococcal enterotoxin B monoclonal antibody that can be repurposed to target the cleavage site of the...

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