Tag : Protein kinases

Biology

Evolution of protein kinase substrate recognition at the active site

Newsemia
by David Bradley, Pedro Beltrao Protein kinases catalyse the phosphorylation of target proteins, controlling most cellular processes. The specificity of serine/threonine kinases is partly determined...
Biology

AMPK regulates germline stem cell quiescence and integrity through an endogenous small RNA pathway

Newsemia
by Pratik Kadekar, Richard Roy During suboptimal growth conditions, Caenorhabditis elegans larvae undergo a global developmental arrest called “dauer.” During this stage, the germline stem...
Biology

Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

Newsemia
by Avnish Patel, Abigail J. Perrin, Helen R. Flynn, Claudine Bisson, Chrislaine Withers-Martinez, Moritz Treeck, Christian Flueck, Giuseppe Nicastro, Stephen R. Martin, Andres Ramos, Tim...
Biology

Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

Newsemia
by Chad J. Miller, Hua Jane Lou, Craig Simpson, Bert van de Kooij, Byung Hak Ha, Oriana S. Fisher, Natasha L. Pirman, Titus J. Boggon,...
Biology

The <i>PLOS Biology</i> XV Collection: 15 Years of Exceptional Science Highlighted across 12 Months

Newsemia
by Lauren A. Richardson, Sandra L. Schmid, Avinash Bhandoola, Christelle Harly, Anders Hedenström, Michael T. Laub, Georgina M. Mace, Piali Sengupta, Ann M. Stock, Andrew...
Biology

MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis

Newsemia
by Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck, Jingwen Yu, Liang Liu, Yvonne Y. C. Yeap, Weiya Zhang, Feng Zhang, Yinghang...
Biology

Integrative network-centric approach reveals signaling pathways associated with plant resistance and susceptibility to <i>Pseudomonas syringae</i>

Newsemia
by Elizabeth K. Brauer, George V. Popescu, Dharmendra K. Singh, Mauricio Calviño, Kamala Gupta, Bhaskar Gupta, Suma Chakravarthy, Sorina C. Popescu Plant protein kinases form...
Biology

Protein kinase A negatively regulates Ca<sup>2+</sup> signalling in <i>Toxoplasma gondii</i>

Newsemia
by Alessandro D. Uboldi, Mary-Louise Wilde, Emi A. McRae, Rebecca J. Stewart, Laura F. Dagley, Luning Yang, Nicholas J. Katris, Sanduni V. Hapuarachchi, Michael J....

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