Tag : Preclinical

Pharma / Biotech

Preclinical pharmacokinetic, biodistribution, radiation dosimetry, and toxicity studies of 99mTc-HYNIC-(Ser)3-LTVPWY: A novel HER2-targeted peptide radiotracer.

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Related Articles Preclinical pharmacokinetic, biodistribution, radiation dosimetry, and toxicity studies of 99mTc-HYNIC-(Ser)3-LTVPWY: A novel HER2-targeted peptide radiotracer. Regul Toxicol Pharmacol. 2020 Jan 29;:104591 Authors: Ardakani...
Pharma / Biotech

Lower Respiratory Tract Delivery, Airway Clearance, and Preclinical Efficacy of Inhaled GM-CSF in a Post-influenza Pneumococcal Pneumonia Model.

Newsemia
Related Articles Lower Respiratory Tract Delivery, Airway Clearance, and Preclinical Efficacy of Inhaled GM-CSF in a Post-influenza Pneumococcal Pneumonia Model. Am J Physiol Lung Cell...
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Study may provide novel targetable mechanisms of therapeutic resistance to anti-VEGF therapies

Newsemia
To establish a molecular signature of this resistance in ovarian cancer, the authors developed preclinical tumor models of adaptive resistance to chronic anti-VEGF treatment. Source...
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Neurofilaments in blood is a new promising preclinical biomarker for the screening of natural scrapie in sheep

Newsemia
Zetterberg, H; Bozzetta, E; Favole, A; Corona, C; Cavarretta, MC; Ingravalle, F; Blennow, K; … Meloni, D; + view all Zetterberg, H; Bozzetta, E; Favole,...
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Synthetic mRNA nanoparticles restore tumor suppressor gene, make cancer cells susceptible to drugs

Newsemia
In preclinical experiments, investigators restored p53 using synthetic mRNA nanoparticles, making lung and liver cancer cells susceptible to available cancer drugs. Source link...
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GB Sciences announces preclinical results of promising formulations for Parkinson's disease

Newsemia
GB Sciences, Inc. announced significant preclinical results for their Parkinson’s disease (“PD”) formulations from the midterm report for their preclinical study being performed by Dr....
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Stoke Therapeutics Presents Preclinical Data From Studies of STK-001 That Showed Improvements in Survival and Reductions in Seizure Frequency in a Mouse Model of Dravet Syndrome

Newsemia
BEDFORD, Mass.–(BUSINESS WIRE)–Stoke Therapeutics, Inc. (Nasdaq:STOK), a biotechnology company pioneering a new way to treat the underlying cause of severe genetic diseases by precisely upregulating...

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