Tag : Polymerase

Biology

CSB-Dependent Cyclin-Dependent Kinase 9 Degradation and RNA Polymerase II Phosphorylation during Transcription-Coupled Repair [Research Article]

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DNA lesions block cellular processes such as transcription, inducing apoptosis, tissue failures, and premature aging. To counteract the deleterious effects of DNA damage, cells are...
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Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome

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Goswami, P; Abid Ali, F; Douglas, ME; Locke, J; Purkiss, A; Janska, A; Eickhoff, P; … Costa, A; + view all Goswami, P; Abid Ali,...
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Xenobiotic Nucleic Acid (XNA) Synthesis by Phi29 DNA Polymerase

Newsemia
Torres, LL; Pinheiro, VB; (2018) Xenobiotic Nucleic Acid (XNA) Synthesis by Phi29 DNA Polymerase. Current Protocols in Chemical Biology , 10 (2) , Article e41....
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Antibiotic found in dirt can destroy mutant mycobacteria responsible for TB, study suggests

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For decades, doctors have been using antibiotics to fight tuberculosis. And consistently, the microbe responsible for the disease, Mycobacterium tuberculosis, has been fighting back. When...

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