Tag : plasma

Pharma / Biotech

Identification of prototypes from Ligustri Lucidi Fructus in rat plasma based on a data-dependent acquisition and multi-components pharmacokinetic study.

Newsemia
Related Articles Identification of prototypes from Ligustri Lucidi Fructus in rat plasma based on a data-dependent acquisition and multi-components pharmacokinetic study. Biomed Chromatogr. 2020 Mar...
Pharma / Biotech

A validated surrogate analyte UPLC-MS/MS assay for quantitation of TUDCA, TCDCA, UDCA, and CDCA in rat plasma: application in a pharmacokinetic study of cultured bear bile powder.

Newsemia
Related Articles A validated surrogate analyte UPLC-MS/MS assay for quantitation of TUDCA, TCDCA, UDCA, and CDCA in rat plasma: application in a pharmacokinetic study of...
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Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

Newsemia
Oncotarget Volume 11, Issue 11 reported that at clinical progression, 64 EGFR T790M plasma positive patients were subjected to second line-treatment with osimertinib and strictly...
Pharma / Biotech

Investigation of plasma concentrations of paracetamol, metacetamol, and orthocetamol in Japanese racehorses using liquid chromatography-electrospray ionisation-tandem mass spectrometry.

Newsemia
Related Articles Investigation of plasma concentrations of paracetamol, metacetamol, and orthocetamol in Japanese racehorses using liquid chromatography-electrospray ionisation-tandem mass spectrometry. Drug Test Anal. 2020 Mar...
Pharma / Biotech

Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration.

Newsemia
Related Articles Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration. Obstet Gynecol. 2020 Mar 10;: Authors: Muhunthan K, Balakumar S, Navaratnaraja TS,...
Pharma / Biotech

Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.

Newsemia
Related Articles Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral...
Pharma / Biotech

Determination of isosinensetin in rat plasma by UHPLC-MS/MS: Application to oral and intravenous pharmacokinetic study in healthy rats.

Newsemia
Related Articles Determination of isosinensetin in rat plasma by UHPLC-MS/MS: Application to oral and intravenous pharmacokinetic study in healthy rats. J Pharm Biomed Anal. 2020...
Pharma / Biotech

Simultaneous determination of ferulic acid, paeoniflorin and albiflorin in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry: Application to a pharmacokinetic study of Danggui-Shaoyao-San.

Newsemia
Related Articles Simultaneous determination of ferulic acid, paeoniflorin and albiflorin in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry: Application to...
Pharma / Biotech

LC-MS/MS determination of buparlisib, a phosphoinositide 3 kinase inhibitor in rat plasma: application to a pharmacokinetic study.

Newsemia
Related Articles LC-MS/MS determination of buparlisib, a phosphoinositide 3 kinase inhibitor in rat plasma: application to a pharmacokinetic study. Biomed Chromatogr. 2020 Feb 28;:e4816 Authors:...
Pharma / Biotech

Simultaneous quantitation of glycyrrhetic acid and puerarin in plasma by UFLC-MS/MS, and application in a pharmacokinetics study in healthy and alcoholic liver injury rats.

Newsemia
Related Articles Simultaneous quantitation of glycyrrhetic acid and puerarin in plasma by UFLC-MS/MS, and application in a pharmacokinetics study in healthy and alcoholic liver injury...
Gastroenterology

Correction: A multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer

Newsemia
Correction: A multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer Source link...
Gastroenterology

TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits ╬│-butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice

Newsemia
The authors identified a metabolite produced by intestinal bacteria, TMAVA, that worsens fatty liver disease by reducing production of the amino acid carnitine. Carnitine might...

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