Tag : physiologically

Pharma / Biotech

Physiologically based pharmacokinetic modeling of lisinopril in children: a case story of angiotensin converting enzyme inhibitors.

Newsemia
Physiologically based pharmacokinetic modeling of lisinopril in children: a case story of angiotensin converting enzyme inhibitors. Br J Clin Pharmacol. 2020 Jul 21;: Authors: Xie...
Pharma / Biotech

Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug-Drug Interactions or in Special Populations: An Example Using Tofacitinib.

Newsemia
Related Articles Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug-Drug Interactions or in Special Populations: An...
Pharma / Biotech

Physiologically Based Pharmacokinetic Modelling of Glycopyrronium in Patients with Renal Impairment.

Newsemia
Related Articles Physiologically Based Pharmacokinetic Modelling of Glycopyrronium in Patients with Renal Impairment. J Pharm Sci. 2020 Mar 30;: Authors: Higashimori M, Ishikawa K, Gillen...
Pharma / Biotech

Pharmacokinetics, Pharmacodynamics and Dermal Distribution of 5-Methoxypsoralen Based on a Physiologically Based Pharmacokinetic Model to Support Phytotherapy Using Brosimum gaudichaudii.

Newsemia
Related Articles Pharmacokinetics, Pharmacodynamics and Dermal Distribution of 5-Methoxypsoralen Based on a Physiologically Based Pharmacokinetic Model to Support Phytotherapy Using Brosimum gaudichaudii. Planta Med. 2020...
Pharma / Biotech

Physiologically based pharmacokinetic modelling of oxycodone drug-drug interactions.

Newsemia
Related Articles Physiologically based pharmacokinetic modelling of oxycodone drug-drug interactions. Biopharm Drug Dispos. 2020 Jan 10;: Authors: Rytkönen J, Ranta VP, Kokki M, Kokki H,...
Pharma / Biotech

Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling.

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Related Articles Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling. J Antimicrob Chemother. 2019 Dec 20;: Authors: Bunglawala...
Pharma / Biotech

Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs using Physiologically based Biopharmaceutics Modeling: Industry Case Studies.

Newsemia
Prediction of pH-Dependent Drug-Drug Interactions for Basic Drugs using Physiologically based Biopharmaceutics Modeling: Industry Case Studies. J Pharm Sci. 2019 Nov 25;: Authors: Mitra A,...
Pharma / Biotech

Development of a physiologically based pharmacokinetic model for intravenous lenalidomide in mice.

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Related Articles Development of a physiologically based pharmacokinetic model for intravenous lenalidomide in mice. Cancer Chemother Pharmacol. 2019 Sep 06;: Authors: Hughes JH, Upton RN,...
Pharma / Biotech

Physiologically based ocular pharmacokinetic modeling using computational methods.

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Related Articles Physiologically based ocular pharmacokinetic modeling using computational methods. Drug Discov Today. 2019 Jul 15;: Authors: Missel PJ, Sarangapani R Abstract Here, we apply...
Pharma / Biotech

A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Model of Dabigatran Etexilate, Dabigatran and Dabigatran Glucuronide in Healthy Adults and Renally Impaired Patients.

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Related Articles A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Model of Dabigatran Etexilate, Dabigatran and Dabigatran Glucuronide in Healthy Adults and Renally Impaired Patients. Clin Pharmacokinet....
Pharma / Biotech

Computer-assembled cross-species/cross-modalities two-pore physiologically based pharmacokinetic model for biologics in mice and rats.

Newsemia
Related Articles Computer-assembled cross-species/cross-modalities two-pore physiologically based pharmacokinetic model for biologics in mice and rats. J Pharmacokinet Pharmacodyn. 2019 May 11;: Authors: Sepp A, Meno-Tetang...
Pharma / Biotech

Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle.

Newsemia
Related Articles Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle. Food Chem Toxicol. 2019...

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