Tag: Phosphorylation

Biology

Differential Phosphorylation of the Transcription Factor WRKY33 by the Protein Kinases CPK5/CPK6 and MPK3/MPK6 Cooperatively Regulates Camalexin Biosynthesis in Arabidopsis

Newsemia
Camalexin is a major phytoalexin that plays a crucial role in disease resistance in Arabidopsis (Arabidopsis thaliana). We previously characterized the regulation of camalexin biosynthesis...
Biology

Cell–substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime

Newsemia
by Shashi Prakash Singh, Peter A. Thomason, Sergio Lilla, Matthias Schaks, Qing Tang, Bruce L. Goode, Laura M. Machesky, Klemens Rottner, Robert H. Insall The...
Latest News

Vitamin D could help suppress excessive T cell-mediated lung inflammation in severe COVID-19

Newsemia
As COVID-19 continues to spread over the world scientists continue to seek the reasons for the difference in disease severity from person to person. Source...
Biology

Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer

Newsemia
by María Gutiérrez-Salmerón, José Manuel García-Martínez, Javier Martínez-Useros, María Jesús Fernández-Aceñero, Benoit Viollet, Severine Olivier, Jagat Chauhan, Silvia R. Lucena, Antonio De la Vieja, Colin...
Latest News

An investigation into the regulation of nPKCs by phosphorylation

Newsemia
Parekh, Davey B.; (2001) An investigation into the regulation of nPKCs by phosphorylation. Doctoral thesis (Ph.D), UCL (University College London). Green open access Source link...
Biology

Nocodazole-Induced Expression and Phosphorylation of Anillin and Other Mitotic Proteins Are Decreased in DNA-Dependent Protein Kinase Catalytic Subunit-Deficient Cells and Rescued by Inhibition of the Anaphase-Promoting Complex/Cyclosome with proTAME but Not Apcin [Research Article]

Newsemia
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) has well-established roles in DNA double-strand break repair, and recently, nonrepair functions have also been reported. To better...
Biology

Mitotic phosphorylation of the ULK complex regulates cell cycle progression

Newsemia
by Akinori Yamasaki, Yui Jin, Yoshinori Ohsumi Autophagy is an intracellular degradation pathway targeting organelles and macromolecules, thereby regulating various cellular functions. Phosphorylation is a...
Biology

ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle

Newsemia
by Zhiyuan Li, Xiaofei Tian, Xinmiao Ji, Junjun Wang, Hanxiao Chen, Dongmei Wang, Xin Zhang Unc-51-like autophagy activating kinase 1 (ULK1)–autophagy-related 13 (ATG13) is the...
Latest News

Study uncovers cause of blood-vessel leakiness in eye diseases

Newsemia
Scientists have identified a key step in the process that leads to leaky vessels and harmful swelling in eye diseases, according to a new study...
Biology

TRAF2 Ser-11 Phosphorylation Promotes Cytosolic Translocation of the CD40 Complex To Regulate Downstream Signaling Pathways [Research Article]

Newsemia
CD40 plays an important role in immune responses by activating the c-Jun N-terminal protein kinase (JNK) and NF-B pathways; however, the precise mechanisms governing the...
Neurology

Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation

Newsemia
Parkinson’s disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). Levodopa (L-Dopa), the current main treatment for...
Neurology

Transformation Foci in IDH1-mutated Gliomas Show STAT3 Phosphorylation and Downregulate the Metabolic Enzyme ETNPPL, a Negative Regulator of Glioma Growth

Newsemia
Transformation Foci in IDH1-mutated Gliomas Show STAT3 Phosphorylation and Downregulate the Metabolic Enzyme ETNPPL, a Negative Regulator of Glioma Growth Source link...

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