Tag : Phosphorylation

Neurology

Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation

Newsemia
Parkinson’s disease (PD) is characterized by progressive degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc). Levodopa (L-Dopa), the current main treatment for...
Neurology

Transformation Foci in IDH1-mutated Gliomas Show STAT3 Phosphorylation and Downregulate the Metabolic Enzyme ETNPPL, a Negative Regulator of Glioma Growth

Newsemia
Transformation Foci in IDH1-mutated Gliomas Show STAT3 Phosphorylation and Downregulate the Metabolic Enzyme ETNPPL, a Negative Regulator of Glioma Growth Source link...
Biology

IL-23 signaling regulation of pro-inflammatory T-cell migration uncovered by phosphoproteomics

Newsemia
by Candelas Álvarez-Salamero, Raquel Castillo-González, Gloria Pastor-Fernández, Isabel R. Mariblanca, Jesús Pino, Danay Cibrian, María N. Navarro Interleukin 23 (IL-23) triggers pathogenic features in pro-inflammatory,...
Biology

Priming Phosphorylation of TANK-Binding Kinase 1 by I{kappa}B Kinase {beta} Is Essential in Toll-Like Receptor 3/4 Signaling [Research Article]

Newsemia
TRIF is an essential adaptor for Toll-like receptor 3/4 (TLR3/4) signaling to activate transcription factor interferon regulatory factor 3 (IRF-3). We examined the molecular mechanism...
Biology

Dynamic Phosphorylation and Dephosphorylation of Cyclase-Associated Protein 1 by Antagonistic Signaling through Cyclin-Dependent Kinase 5 and cAMP Are Critical for the Protein Functions in Actin Filament Disassembly and Cell Adhesion [Research Article]

Newsemia
Cyclase-associated protein 1 (CAP1) is a conserved actin-regulating protein that enhances actin filament dynamics and also regulates adhesion in mammalian cells. We previously found that...
Latest News

Scientists discover potential drug compounds that target common type of liver cancer

Newsemia
Scientists from the Cancer Science Institute of Singapore at the National University of Singapore, and the Agency for Science, Technology and Research (A*STAR)’s Genome Institute...
Biology

Photosensing and quorum sensing are integrated to control <i>Pseudomonas aeruginosa</i> collective behaviors

Newsemia
by Sampriti Mukherjee, Matthew Jemielita, Vasiliki Stergioula, Mikhail Tikhonov, Bonnie L. Bassler Bacteria convert changes in sensory inputs into alterations in gene expression, behavior, and...
Biology

BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics

Newsemia
by Christian Hiepen, Jerome Jatzlau, Susanne Hildebrandt, Branka Kampfrath, Melis Goktas, Arunima Murgai, Jose Luis Cuellar Camacho, Rainer Haag, Clemens Ruppert, Gerhard Sengle, Elisabetta Ada...
Biology

Loss of adenomatous polyposis coli function renders intestinal epithelial cells resistant to the cytokine IL-22

Newsemia
by Yu Chen, Maud Vandereyken, Ian P. Newton, Ignacio Moraga, Inke S. Näthke, Mahima Swamy Interleukin-22 (IL-22) is a critical immune defence cytokine that maintains...
Cardiology

A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation.

Newsemia
A histone deacetylase 7-derived peptide promotes vascular regeneration via facilitating 14-3-3γ phosphorylation. Stem Cells. 2019 Nov 13;: Authors: Yang J, Moraga A, Xu J, Zhao...
Biology

Yeast α-arrestin Art2 is the key regulator of ubiquitylation-dependent endocytosis of plasma membrane vitamin B1 transporters

Newsemia
by Jérôme Savocco, Sylvain Nootens, Wilhelmine Afokpa, Mathilde Bausart, Xiaoqian Chen, Jennifer Villers, Henri-François Renard, Martine Prévost, Ruddy Wattiez, Pierre Morsomme Endocytosis of membrane proteins...

This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Accept Read More

Privacy & Cookies Policy