Tag : phosphatase

Biology

GP78 Cooperates with Dual-Specificity Phosphatase 1 To Stimulate Epidermal Growth Factor Receptor-Mediated Extracellular Signal-Regulated Kinase Signaling [Research Article]

Newsemia
GP78 is an autocrine motility factor (AMF) receptor (AMFR) with E3 ubiquitin ligase activity that plays a significant role in tumor cell proliferation, motility, and...
Biology

Expression of Concern for Lee et al., "Overexpression of Kinase-Associated Phosphatase (KAP) in Breast and Prostate Cancer and Inhibition of the Transformed Phenotype by Antisense KAP Expression" [Expression Of Concern]

Newsemia
Expression of Concern for Lee et al., "Overexpression of Kinase-Associated Phosphatase (KAP) in Breast and Prostate Cancer and Inhibition of the Transformed Phenotype by Antisense...
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FDA approves LORBRENA for treatment of patients with ALK-positive metastatic NSCLC

Newsemia
Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved LORBRENA, a third-generation anaplastic lymphoma kinase tyrosine kinase inhibitor for patients with...
Biology

Protein Phosphatase 1{alpha} and Cofilin Regulate Nuclear Translocation of NF-{kappa}B and Promote Expression of the Anti-Inflammatory Cytokine Interleukin-10 by T Cells [Research Article]

Newsemia
While several protein serine/threonine kinases control cytokine production by T cells, the roles of serine/threonine phosphatases are largely unexplored. Here, we analyzed the involvement of...

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