Tag: pharmacokinetic

Pharma / Biotech

Pharmacokinetic Investigation of Synthetic Cannabidiol Oral Formulations in Healthy Volunteers.

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Related Articles Pharmacokinetic Investigation of Synthetic Cannabidiol Oral Formulations in Healthy Volunteers. Eur J Pharm Biopharm. 2020 Jul 04;: Authors: Izgelov D, Davidson E, Barasch...
Pharma / Biotech

The SNAP 101 Double-Blind, Placebo/Active-Controlled, Safety, Pharmacokinetic, and Pharmacodynamic Study of INP105 (Nasal Olanzapine) in Healthy Adults.

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Related Articles The SNAP 101 Double-Blind, Placebo/Active-Controlled, Safety, Pharmacokinetic, and Pharmacodynamic Study of INP105 (Nasal Olanzapine) in Healthy Adults. J Clin Psychiatry. 2020 Jun 30;81(4):...
Pharma / Biotech

Pharmacokinetic study (phase I-II) of a new dobutamine formulation in preterm infants immediately after birth.

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Related Articles Pharmacokinetic study (phase I-II) of a new dobutamine formulation in preterm infants immediately after birth. Pediatr Res. 2020 Jul 01;: Authors: Pellicer A,...
Pharma / Biotech

Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug-Drug Interactions or in Special Populations: An Example Using Tofacitinib.

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Related Articles Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug-Drug Interactions or in Special Populations: An...
Cardiology

Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor.

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Related Articles Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor. Biomed Pharmacother. 2020 Jun 19;129:110410 Authors: Sun J, Xu W, Hua...
Pharma / Biotech

Evaluation of the Potential Pharmacokinetic Interactions Between Vixotrigine and an Oral Contraceptive.

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Related Articles Evaluation of the Potential Pharmacokinetic Interactions Between Vixotrigine and an Oral Contraceptive. Clin Drug Investig. 2020 Jun 20;: Authors: Zhao Y, Versavel M,...
Pharma / Biotech

Prior information for population pharmacokinetic and pharmacokinetic/pharmacodynamic analysis: overview and guidance with a focus on the NONMEM PRIOR subroutine.

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Related Articles Prior information for population pharmacokinetic and pharmacokinetic/pharmacodynamic analysis: overview and guidance with a focus on the NONMEM PRIOR subroutine. J Pharmacokinet Pharmacodyn. 2020...
Pharma / Biotech

Simultaneous determination of nineteen compounds of Dahuang zhechong pill in rat plasma by UHPLC-MS/MS and its application in a pharmacokinetic study.

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Related Articles Simultaneous determination of nineteen compounds of Dahuang zhechong pill in rat plasma by UHPLC-MS/MS and its application in a pharmacokinetic study. J Chromatogr...
Pharma / Biotech

Development and validation of a LC-MS/MS method for simultaneous determination of TQ-A3326 and its major metabolites in human plasma, urine and feces: application to pharmacokinetic assay.

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Related Articles Development and validation of a LC-MS/MS method for simultaneous determination of TQ-A3326 and its major metabolites in human plasma, urine and feces: application...
Pharma / Biotech

Development of a novel tandem mass spectrometry method for the quantification of eszopiclone without interference from 2-amino-5-chloropyridine and application in a pharmacokinetic study of rat.

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Related Articles Development of a novel tandem mass spectrometry method for the quantification of eszopiclone without interference from 2-amino-5-chloropyridine and application in a pharmacokinetic study...
Pharma / Biotech

Pharmacokinetic and bioavailability studies of α-viniferin after intravenous and oral administration to rats.

Newsemia
Related Articles Pharmacokinetic and bioavailability studies of α-viniferin after intravenous and oral administration to rats. J Pharm Biomed Anal. 2020 May 25;188:113376 Authors: Fan Y,...
Pharma / Biotech

Stereoselective pharmacokinetic study of epiprogoitrin and progoitrin in rats with UHPLC-MS/MS method.

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Related Articles Stereoselective pharmacokinetic study of epiprogoitrin and progoitrin in rats with UHPLC-MS/MS method. J Pharm Biomed Anal. 2020 May 07;187:113356 Authors: Xu Y, Li...
Pharma / Biotech

Trimethyl chitosan nanoparticles for ocular baicalein delivery: Preparation, optimization, in vitro evaluation, in vivo pharmacokinetic study and molecular dynamics simulation.

Newsemia
Related Articles Trimethyl chitosan nanoparticles for ocular baicalein delivery: Preparation, optimization, in vitro evaluation, in vivo pharmacokinetic study and molecular dynamics simulation. Int J Biol...
Pharma / Biotech

Carboxyvinyl Polymer and Guar-Borate Gelling System Containing Natamycin Loaded PEGylated Nanolipid Carriers Exhibit Improved Ocular Pharmacokinetic Parameters.

Newsemia
Related Articles Carboxyvinyl Polymer and Guar-Borate Gelling System Containing Natamycin Loaded PEGylated Nanolipid Carriers Exhibit Improved Ocular Pharmacokinetic Parameters. J Ocul Pharmacol Ther. 2020 Apr...
Pharma / Biotech

Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties.

Newsemia
Related Articles Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties. Clin Pharmacokinet. 2020 Apr 18;: Authors: Smit C, Peeters MYM, van den...
Pharma / Biotech

The association between anti-insulin aspart antibodies and the pharmacokinetic and pharmacodynamic characteristics of fast-acting insulin aspart in children and adolescents with type 1 diabetes.

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Related Articles The association between anti-insulin aspart antibodies and the pharmacokinetic and pharmacodynamic characteristics of fast-acting insulin aspart in children and adolescents with type 1...
Pharma / Biotech

Development and Validation of an HPLC Method for Quantification of Filgotinib, a Novel JAK-1 Inhibitor in Mice Plasma: Application to a Pharmacokinetic Study.

Newsemia
Development and Validation of an HPLC Method for Quantification of Filgotinib, a Novel JAK-1 Inhibitor in Mice Plasma: Application to a Pharmacokinetic Study. Drug Res...
Pharma / Biotech

Guidelines for the experimental design of pharmacokinetic studies with nanomaterials in preclinical animal models.

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Related Articles Guidelines for the experimental design of pharmacokinetic studies with nanomaterials in preclinical animal models. J Control Release. 2020 Apr 09;: Authors: Valic MS,...
Pharma / Biotech

Quantitative pharmacokinetic evaluation of Subtilisin QK-2 after a bolus IV injection in a rat model using a novel sandwich enzyme-linked immunosorbent assay.

Newsemia
Related Articles Quantitative pharmacokinetic evaluation of Subtilisin QK-2 after a bolus IV injection in a rat model using a novel sandwich enzyme-linked immunosorbent assay. J...
Pharma / Biotech

Development an UPLC-ESI-Orbitrap MS method for determination of xanthopurpurin in rat plasma and its application to pharmacokinetic study.

Newsemia
Related Articles Development an UPLC-ESI-Orbitrap MS method for determination of xanthopurpurin in rat plasma and its application to pharmacokinetic study. Biomed Chromatogr. 2020 Apr 04;:e4838...

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