Tag : pharmacokinetic

Pharma / Biotech

Development an UPLC-ESI-Orbitrap MS method for determination of xanthopurpurin in rat plasma and its application to pharmacokinetic study.

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Related Articles Development an UPLC-ESI-Orbitrap MS method for determination of xanthopurpurin in rat plasma and its application to pharmacokinetic study. Biomed Chromatogr. 2020 Apr 04;:e4838...
Pharma / Biotech

Simultaneous determination of six components of Danzhi Xiaoyao Pill in beagle plasma by HPLC-MS/MS and a study of pharmacokinetic of paeoniflorin and geniposide after single-dose administration.

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Related Articles Simultaneous determination of six components of Danzhi Xiaoyao Pill in beagle plasma by HPLC-MS/MS and a study of pharmacokinetic of paeoniflorin and geniposide...
Pharma / Biotech

Physiologically Based Pharmacokinetic Modelling of Glycopyrronium in Patients with Renal Impairment.

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Related Articles Physiologically Based Pharmacokinetic Modelling of Glycopyrronium in Patients with Renal Impairment. J Pharm Sci. 2020 Mar 30;: Authors: Higashimori M, Ishikawa K, Gillen...
Pharma / Biotech

Population pharmacokinetic analysis of esomeprazole in Japanese subjects with various CYP2C19 phenotypes.

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Related Articles Population pharmacokinetic analysis of esomeprazole in Japanese subjects with various CYP2C19 phenotypes. J Clin Pharm Ther. 2020 Mar 30;: Authors: Nagase M, Shimada...
Pharma / Biotech

A Practice-Based, Clinical Pharmacokinetic Study to Inform Levetiracetam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemofiltration (PADRE-01).

Newsemia
Related Articles A Practice-Based, Clinical Pharmacokinetic Study to Inform Levetiracetam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemofiltration (PADRE-01). Clin Transl Sci. 2020 Mar...
Pharma / Biotech

Effect of Co-Administration of Acori Tatarinowii Rhizoma volatile oil on pharmacokinetic fate of xanthotoxol, oxypeucedanin hydrate and byakangelicin from Angelicae Dahuricae Radix in rat.

Newsemia
Related Articles Effect of Co-Administration of Acori Tatarinowii Rhizoma volatile oil on pharmacokinetic fate of xanthotoxol, oxypeucedanin hydrate and byakangelicin from Angelicae Dahuricae Radix in...
Pharma / Biotech

Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: a Pharmacokinetic, Microbiome and Untargeted Metabolomics Study.

Newsemia
Related Articles Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: a Pharmacokinetic, Microbiome and Untargeted Metabolomics Study. Clin Transl Sci. 2020...
Pharma / Biotech

Identification of prototypes from Ligustri Lucidi Fructus in rat plasma based on a data-dependent acquisition and multi-components pharmacokinetic study.

Newsemia
Related Articles Identification of prototypes from Ligustri Lucidi Fructus in rat plasma based on a data-dependent acquisition and multi-components pharmacokinetic study. Biomed Chromatogr. 2020 Mar...
Pharma / Biotech

A validated surrogate analyte UPLC-MS/MS assay for quantitation of TUDCA, TCDCA, UDCA, and CDCA in rat plasma: application in a pharmacokinetic study of cultured bear bile powder.

Newsemia
Related Articles A validated surrogate analyte UPLC-MS/MS assay for quantitation of TUDCA, TCDCA, UDCA, and CDCA in rat plasma: application in a pharmacokinetic study of...
Pharma / Biotech

Determination of Oroxylin A, Oroxylin A 7-O-glucuronide, and Oroxylin A sodium sulfonate in beagle dogs via ultra-high-performance liquid chromatography/tandem mass spectrometry: Application in a pharmacokinetic study.

Newsemia
Related Articles Determination of Oroxylin A, Oroxylin A 7-O-glucuronide, and Oroxylin A sodium sulfonate in beagle dogs via ultra-high-performance liquid chromatography/tandem mass spectrometry: Application in...
Pharma / Biotech

Pharmacokinetic and Metabolic Profile of Deutetrabenazine (TEV-50717) Compared With Tetrabenazine in Healthy Volunteers.

Newsemia
Related Articles Pharmacokinetic and Metabolic Profile of Deutetrabenazine (TEV-50717) Compared With Tetrabenazine in Healthy Volunteers. Clin Transl Sci. 2020 Mar 10;: Authors: Schneider F, Bradbury...
Pharma / Biotech

Population pharmacokinetic and exposure-response analysis of eptinezumab in the treatment of episodic and chronic migraine.

Newsemia
Related Articles Population pharmacokinetic and exposure-response analysis of eptinezumab in the treatment of episodic and chronic migraine. Pharmacol Res Perspect. 2020 Apr;8(2):e00567 Authors: Baker B,...
Pharma / Biotech

Effects of multidose simvastatin co-administration on pharmacokinetic profile of apatinib in rats by UPLC-MS/MS.

Newsemia
Related Articles Effects of multidose simvastatin co-administration on pharmacokinetic profile of apatinib in rats by UPLC-MS/MS. Xenobiotica. 2020 Mar 09;:1-21 Authors: Gao J, Ren H,...
Pharma / Biotech

Considerations for pharmacokinetic assessment of immunoglobulins: Gammagard in very low birth weight neonates with and without baseline-correction.

Newsemia
Related Articles Considerations for pharmacokinetic assessment of immunoglobulins: Gammagard in very low birth weight neonates with and without baseline-correction. Int Immunopharmacol. 2020 Mar 02;82:106358 Authors:...
Pharma / Biotech

Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations.

Newsemia
Related Articles Phase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent Populations. Drugs R D. 2020 Mar 04;:...
Pharma / Biotech

Determination of isosinensetin in rat plasma by UHPLC-MS/MS: Application to oral and intravenous pharmacokinetic study in healthy rats.

Newsemia
Related Articles Determination of isosinensetin in rat plasma by UHPLC-MS/MS: Application to oral and intravenous pharmacokinetic study in healthy rats. J Pharm Biomed Anal. 2020...
Pharma / Biotech

Investigation of pre-clinical pharmacokinetic parameters of atovaquone nanosuspension prepared using pH based precipitation method and its pharmacodynamic properties in a novel artemisinin combination.

Newsemia
Related Articles Investigation of pre-clinical pharmacokinetic parameters of atovaquone nanosuspension prepared using pH based precipitation method and its pharmacodynamic properties in a novel artemisinin combination....
Pharma / Biotech

Simultaneous determination of ferulic acid, paeoniflorin and albiflorin in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry: Application to a pharmacokinetic study of Danggui-Shaoyao-San.

Newsemia
Related Articles Simultaneous determination of ferulic acid, paeoniflorin and albiflorin in rat plasma by ultra high performance liquid chromatography with tandem mass spectrometry: Application to...
Pharma / Biotech

Pharmacokinetic profiles of amoxicillin trihydrate in freshwater crocodiles (Crocodylus siamensis) after intramuscular administration at two doses.

Newsemia
Related Articles Pharmacokinetic profiles of amoxicillin trihydrate in freshwater crocodiles (Crocodylus siamensis) after intramuscular administration at two doses. J Vet Pharmacol Ther. 2020 Feb 29;:...

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