Tag : Pharmacodynamics

Pharma / Biotech

Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction.

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Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction. Neuropsychopharmacology. 2020 Jul 30;: Authors: Canchy L, Girardeau P, Durand A,...
Pharma / Biotech

Pharmacokinetics and pharmacodynamics of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs.

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Related Articles Pharmacokinetics and pharmacodynamics of a novel analgesic with a deterrent to human opioid abuse (methadone-fluconazole-naltrexone) after oral administration in dogs. Am J Vet...
Pharma / Biotech

The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive – A randomized controlled trial.

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Related Articles The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive – A randomized controlled trial. Br J Clin Pharmacol....
Pharma / Biotech

First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G-protein-biased Sphingosine-1 phosphate receptor-1 agonist for endothelial protection.

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Related Articles First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of single and multiple oral doses of SAR247799, a selective G-protein-biased Sphingosine-1 phosphate receptor-1...
Pharma / Biotech

Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Infliximab in Pediatric Inflammatory Bowel Disease: A Systematic Review and Revised Dosing Considerations.

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Related Articles Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Infliximab in Pediatric Inflammatory Bowel Disease: A Systematic Review and Revised Dosing Considerations. J Pediatr Gastroenterol Nutr. 2020...
Pharma / Biotech

Safety, tolerability, pharmacokinetics, and pharmacodynamics of macimorelin in healthy adults: Results of a single-dose, randomized controlled study.

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of macimorelin in healthy adults: Results of a single-dose, randomized controlled study. Growth Horm IGF Res. 2020 Apr 15;52:101321 Authors:...
Pharma / Biotech

Pharmacokinetics and pharmacodynamics of a single dose of sustained-release azithromycin formulation in pigeons.

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Related Articles Pharmacokinetics and pharmacodynamics of a single dose of sustained-release azithromycin formulation in pigeons. Pol J Vet Sci. 2020 Mar;23(1):43-50 Authors: Zań R, Burmańczuk...
Pharma / Biotech

Safety, Pharmacokinetics and Pharmacodynamics of Branebrutinib (BMS-986195), a Covalent, Irreversible Inhibitor of Bruton's Tyrosine Kinase: Randomised Phase I, Placebo-Controlled Trial in Healthy Participants.

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Safety, Pharmacokinetics and Pharmacodynamics of Branebrutinib (BMS-986195), a Covalent, Irreversible Inhibitor of Bruton’s Tyrosine Kinase: Randomised Phase I, Placebo-Controlled Trial in Healthy Participants. Br J...
Pharma / Biotech

Pharmacokinetics and Pharmacodynamics of Ursodeoxycholic Acid in an Overweight Population With Abnormal Liver Function.

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Related Articles Pharmacokinetics and Pharmacodynamics of Ursodeoxycholic Acid in an Overweight Population With Abnormal Liver Function. Clin Pharmacol Drug Dev. 2020 Mar 19;: Authors: Yoon...
Pharma / Biotech

The effect of cardiac output on the pharmacokinetics and pharmacodynamics of propofol during closed-loop induction of anesthesia.

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Related Articles The effect of cardiac output on the pharmacokinetics and pharmacodynamics of propofol during closed-loop induction of anesthesia. Comput Methods Programs Biomed. 2020 Feb...
Pharma / Biotech

Effect of Post-dose Fasting Duration on Hetrombopag Olamine Pharmacokinetics and Pharmacodynamics in Healthy Volunteers.

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Related Articles Effect of Post-dose Fasting Duration on Hetrombopag Olamine Pharmacokinetics and Pharmacodynamics in Healthy Volunteers. Br J Clin Pharmacol. 2020 Feb 18;: Authors: Yang...
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Role of rutin nanoemulsion in ameliorating oxidative stress: Pharmacokinetic and Pharmacodynamics studies.

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Related Articles Role of rutin nanoemulsion in ameliorating oxidative stress: Pharmacokinetic and Pharmacodynamics studies. Chem Phys Lipids. 2020 Feb 04;:104890 Authors: Sharma S, Rabbani SA,...
Pharma / Biotech

Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers: Part I. Pharmacokinetics and Clinical Pharmacodynamics.

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Related Articles Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers: Part I. Pharmacokinetics and Clinical Pharmacodynamics. Anesthesiology. 2020 Jan...
Pharma / Biotech

Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers: Part II. Pharmacodynamics of Electroencephalogram Effects.

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Related Articles Pharmacokinetics and Pharmacodynamics of Remimazolam (CNS 7056) after Continuous Infusion in Healthy Male Volunteers: Part II. Pharmacodynamics of Electroencephalogram Effects. Anesthesiology. 2020 Jan...
Pharma / Biotech

Pharmacokinetics, Pharmacodynamics and Dermal Distribution of 5-Methoxypsoralen Based on a Physiologically Based Pharmacokinetic Model to Support Phytotherapy Using Brosimum gaudichaudii.

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Related Articles Pharmacokinetics, Pharmacodynamics and Dermal Distribution of 5-Methoxypsoralen Based on a Physiologically Based Pharmacokinetic Model to Support Phytotherapy Using Brosimum gaudichaudii. Planta Med. 2020...
Pharma / Biotech

Pharmacokinetics, Pharmacodynamics and Safety of Belimumab in Chinese Patients with Systemic Lupus Erythematosus: A Phase I, Open-Label Study.

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Related Articles Pharmacokinetics, Pharmacodynamics and Safety of Belimumab in Chinese Patients with Systemic Lupus Erythematosus: A Phase I, Open-Label Study. Rheumatol Ther. 2020 Jan 17;: Authors:...
Pharma / Biotech

Effect of Smoking Cessation on the Pharmacokinetics and Pharmacodynamics of Clopidogrel after PCI: The Smoking Cessation Paradox Study.

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Effect of Smoking Cessation on the Pharmacokinetics and Pharmacodynamics of Clopidogrel after PCI: The Smoking Cessation Paradox Study. Thromb Haemost. 2020 Jan 15;: Authors: Ramotowski...

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