Tag: PCSK9

Neurology

Silencing Novel Target Genes: A New Strategy for Lipid Lowering

Newsemia
Following in the footsteps of inclisiran, two lipid-lowering therapies based on silencing specific genes involved in lipid metabolism showed promising preliminary results in initial clinical...
Neurology

ORION-10: 58% Reduction in LDL With Inclisiran

Newsemia
A second phase 3 study has shown impressive reductions in LDL on top of statins with this novel agent given just twice a year. Medscape...
Neurology

'Double Whammy': Where do PCSK9 Inhibitors Fit for Diabetes/ACS?

Newsemia
Patients with diabetes as well as ACS and uncontrolled high cholesterol have a "double whammy" that makes them candidates for PCSK9 inhibitors to prevent CV...
Neurology

Factors Linked to LDL-Cholesterol Levels Differ by Gender

Newsemia
Different impact of lifestyle and genetic factors on LDL-cholesterol levels in men and women could have ‘strong repercussions’ for treatment, researchers say. Medscape Medical News...
Neurology

Fixed-Dose Bempedoic Acid, Ezetimibe Combo for Statin Intolerance?

Newsemia
The fixed-dose combination of the complementary drugs is ‘potent and convenient,’ researchers conclude, with statin intolerance potentially ‘a very nice niche.’ Medscape Medical News Source...

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