Tag: Pathogenic

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Study shows how protective T cells become pathogenic in atherosclerosis

Newsemia
High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in...
Cardiology

Overlapping pathogenic signalling pathways and biomarkers in preeclampsia and cardiovascular disease.

Newsemia
Related Articles Overlapping pathogenic signalling pathways and biomarkers in preeclampsia and cardiovascular disease. Pregnancy Hypertens. 2020 Mar 29;20:131-136 Authors: Suvakov S, Bonner E, Nikolic V,...
Cardiology

A Three-Part, Randomised Study to Investigate the Safety, Tolerability, Pharmacokinetics and Mode of Action of BC 007, Neutraliser of Pathogenic Autoantibodies Against G-Protein Coupled Receptors in Healthy, Young and Elderly Subjects.

Newsemia
Related Articles A Three-Part, Randomised Study to Investigate the Safety, Tolerability, Pharmacokinetics and Mode of Action of BC 007, Neutraliser of Pathogenic Autoantibodies Against G-Protein...
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Pathogenic Activation of Mesenchymal Stem Cells is induced by the Disease Microenvironment in Systemic Sclerosis

Newsemia
Stratton, R; Taki, Z; Denton, C; Ahmed Abdi, B; (2020) Pathogenic Activation of Mesenchymal Stem Cells is induced by the Disease Microenvironment in Systemic Sclerosis....
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Quantitative Approach to Fragmented QRS in Arrhythmogenic Cardiomyopathy: From Disease towards Asymptomatic Carriers of Pathogenic Variants

Newsemia
Roudijk, RW; Bosman, LP; van der Heijden, JF; de Bakker, JMT; Hauer, RNW; van Tintelen, JP; Asselbergs, FW; … Loh, P; + view all Roudijk,...
Cardiology

Exome-Based Case-Control Analysis Highlights the Pathogenic Role of Ciliary Genes in Transposition of the Great Arteries.

Newsemia
Related Articles Exome-Based Case-Control Analysis Highlights the Pathogenic Role of Ciliary Genes in Transposition of the Great Arteries. Circ Res. 2020 Feb 11;: Authors: Liu...
Gastroenterology

12 A FUNCTIONAL TL1A/DR3 SYSTEM IS CRUCIAL FOR OPTIMAL GENERATION OF PATHOGENIC TH9 CELLS IN MURINE CROHN'S DISEASE-LIKE ILEITIS

Newsemia
Despite numerous therapeutic advancements, inflammatory bowel disease (IBD) remains a major health burden due to the inefficiency of conventional therapies. We recently demonstrated the role...
Gastroenterology

Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

Newsemia
Lynch syndrome is caused by alterations in a specific group of genes. Patients with different types of genetic alterations develop adenomas and CRC at different...
Cardiology

Predicted pathogenic mutations in STAP1 are not associated with clinically defined familial hypercholesterolemia.

Newsemia
Related Articles Predicted pathogenic mutations in STAP1 are not associated with clinically defined familial hypercholesterolemia. Atherosclerosis. 2019 Nov 29;292:143-151 Authors: Lamiquiz-Moneo I, Restrepo-Córdoba MA, Mateo-Gallego...

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