Tag: Parasitic diseases

Biology

Genetic and functional diversification of chemosensory pathway receptors in mosquito-borne filarial nematodes

Newsemia
by Nicolas J. Wheeler, Zachary W. Heimark, Paul M. Airs, Alexis Mann, Lyric C. Bartholomay, Mostafa Zamanian Lymphatic filariasis (LF) afflicts over 60 million people...
Biology

Single-cell transcription analysis of <i>Plasmodium vivax</i> blood-stage parasites identifies stage- and species-specific profiles of expression

Newsemia
by Juliana M. Sà, Matthew V. Cannon, Ramoncito L. Caleon, Thomas E. Wellems, David Serre Plasmodium vivax and P. falciparum, the parasites responsible for most...
Biology

Resurrection of the ancestral RH5 invasion ligand provides a molecular explanation for the origin of <i>P. falciparum</i> malaria in humans

Newsemia
by Francis Galaway, Ryan Yu, Anastasia Constantinou, Franck Prugnolle, Gavin J. Wright Many important infectious diseases are the result of zoonoses, in which pathogens that...
Biology

A rotifer-derived paralytic compound prevents transmission of schistosomiasis to a mammalian host

Newsemia
by Jiarong Gao, Ning Yang, Fred A. Lewis, Peter Yau, James J. Collins III, Jonathan V. Sweedler, Phillip A. Newmark Schistosomes are parasitic flatworms that...
Biology

Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in <i>Plasmodium falciparum</i>

Newsemia
by Shai Pilosof, Qixin He, Kathryn E. Tiedje, Shazia Ruybal-Pesántez, Karen P. Day, Mercedes Pascual In their competition for hosts, parasites with antigens that are...
Biology

Rapid antigen diversification through mitotic recombination in the human malaria parasite <i>Plasmodium falciparum</i>

Newsemia
by Xu Zhang, Noah Alexander, Irina Leonardi, Christopher Mason, Laura A. Kirkman, Kirk W. Deitsch Malaria parasites possess the remarkable ability to maintain chronic infections...
Biology

Systematically improved in vitro culture conditions reveal new insights into the reproductive biology of the human parasite <i>Schistosoma mansoni</i>

Newsemia
by Jipeng Wang, Rui Chen, James J. Collins III Schistosomes infect over 200 million people. The prodigious egg output of these parasites is the sole...
Biology

Resolving the apparent transmission paradox of African sleeping sickness

Newsemia
by Paul Capewell, Katie Atkins, William Weir, Vincent Jamonneau, Mamadou Camara, Caroline Clucas, Nono-Raymond K. Swar, Dieudonne M. Ngoyi, Brice Rotureau, Paul Garside, Alison P....
Biology

Resistance gained, resistance lost: An explanation for host–parasite coexistence

Newsemia
by Britt Koskella Host populations are under continual selection by parasites due to reduced fitness of infected individuals relative to uninfected individuals. This should select...
Biology

Protein kinase A negatively regulates Ca<sup>2+</sup> signalling in <i>Toxoplasma gondii</i>

Newsemia
by Alessandro D. Uboldi, Mary-Louise Wilde, Emi A. McRae, Rebecca J. Stewart, Laura F. Dagley, Luning Yang, Nicholas J. Katris, Sanduni V. Hapuarachchi, Michael J....
Biology

Within-host competition can delay evolution of drug resistance in malaria

Newsemia
by Mary Bushman, Rustom Antia, Venkatachalam Udhayakumar, Jacobus C. de Roode In the malaria parasite P. falciparum, drug resistance generally evolves first in low-transmission settings,...
Biology

<i>Plasmodium vivax</i>-like genome sequences shed new insights into <i>Plasmodium vivax</i> biology and evolution

Newsemia
by Aude Gilabert, Thomas D. Otto, Gavin G. Rutledge, Blaise Franzon, Benjamin Ollomo, Céline Arnathau, Patrick Durand, Nancy D. Moukodoum, Alain-Prince Okouga, Barthélémy Ngoubangoye, Boris...
Biology

<i>Plasmodium vivax</i>-like genome sequences shed new insights into <i>Plasmodium vivax</i> biology and evolution

Newsemia
by Aude Gilabert, Thomas D. Otto, Gavin G. Rutledge, Blaise Franzon, Benjamin Ollomo, Céline Arnathau, Patrick Durand, Nancy D. Moukodoum, Alain-Prince Okouga, Barthélémy Ngoubangoye, Boris...
Biology

Within-host competition can delay evolution of drug resistance in malaria

Newsemia
by Mary Bushman, Rustom Antia, Venkatachalam Udhayakumar, Jacobus C. de Roode In the malaria parasite P. falciparum, drug resistance generally evolves first in low-transmission settings,...
Biology

Inter-subunit interactions drive divergent dynamics in mammalian and <i>Plasmodium</i> actin filaments

Newsemia
by Ross G. Douglas, Prajwal Nandekar, Julia-Elisabeth Aktories, Hirdesh Kumar, Rebekka Weber, Julia M. Sattler, Mirko Singer, Simone Lepper, S. Kashif Sadiq, Rebecca C. Wade,...

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