Tag : p38

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Blocking elevated p38 MAPK restores efferocytosis and inflammatory resolution in the elderly

Newsemia
Gilroy, D; De Maeyer, R; Van De Merwe, R; Louie, R; Bracken, O; Devine, O; Goldstein, D; … Akbar, A; + view all Gilroy, D;...
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Crosstalk between Nodal/Activin and MAPK p38 Signaling Is Essential for Anterior-Posterior Axis Specification

Newsemia
Clements, M; Pernaute, B; Vella, F; Rodriguez, TA; (2011) Crosstalk between Nodal/Activin and MAPK p38 Signaling Is Essential for Anterior-Posterior Axis Specification. Current Biology ,...
Cardiology

Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling.

Newsemia
Related Articles Nicotinamide riboside kinase-2 alleviates ischemia-induced heart failure through P38 signaling. Biochim Biophys Acta Mol Basis Dis. 2019 Nov 16;:165609 Authors: Ahmad F, Tomar...
Pharma / Biotech

A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib in patients with advanced or metastatic cancer.

Newsemia
Related Articles A phase 1 dose-escalation study of checkpoint kinase 1 (CHK1) inhibitor prexasertib in combination with p38 mitogen-activated protein kinase (p38 MAPK) inhibitor ralimetinib...
Biology

Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport [Research Article]

Newsemia
The p38 signal transduction pathway can be activated transiently or constitutively, depending on the contexts in which the activation occurs. However, the biological consequence of...

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