Tag : oncogenic

Neurology

Glioblastoma-Derived Extracellular Vesicles Facilitate Transformation of Astrocytes via Reprogramming Oncogenic Metabolism.

Newsemia
Glioblastoma-Derived Extracellular Vesicles Facilitate Transformation of Astrocytes via Reprogramming Oncogenic Metabolism. iScience. 2020 Jul 29;23(8):101420 Authors: Zeng A, Wei Z, Rabinovsky R, Jun HJ, El...
Biology

FCHSD2 controls oncogenic ERK1/2 signaling outcome by regulating endocytic trafficking

Newsemia
by Guan-Yu Xiao, Sandra L. Schmid The evolution of transformed cancer cells into metastatic tumors is, in part, driven by altered intracellular signaling downstream of...
Gastroenterology

Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes

Newsemia
The β-catenin signaling pathway is one of the most commonly deregulated pathways in cancer cells. Amino-acid substitutions within armadillo repeats 5 and 6 (K335, W383,...

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