Tag : Nucleases

Biology

A compact Cas9 ortholog from <i>Staphylococcus Auricularis</i> (SauriCas9) expands the DNA targeting scope

Newsemia
by Ziying Hu, Shuai Wang, Chengdong Zhang, Ning Gao, Miaomiao Li, Deqian Wang, Daqi Wang, Dong Liu, Huihui Liu, Sang-Ging Ong, Hongyan Wang, Yongming Wang...
Biology

Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease

Newsemia
by Weizhong Chen, Hongyuan Zhang, Yifei Zhang, Yu Wang, Jianhua Gan, Quanjiang Ji Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have been harnessed as...
Latest News

Sangamo Announces Nature Biotechnology Publication of New Strategies for Optimizing the Specificity of Gene Editing Nucleases

Newsemia
BRISBANE, Calif.–(BUSINESS WIRE)–Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, announced today the publication in Nature Biotechnology of a manuscript by Jeffrey Miller, Ph.D.,...

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